BSG/ACPGBI guidance on the management of colorectal polyps in patients with limited life expectancy

Abstract


Background
Determining optimal management of colorectal polyps in patients with limited life expectancy of under 10 years can be difficult, due to challenges balancing an uncertain natural history of polyp progression to symptomatic malignancy versus the increased risk and consequences of polypectomy complications.

Aim
This British Society of Gastroenterology and Association of Coloproctologists of Great Britain and Ireland guidance aims to help clinicians and patients consider these risks to aid decision-making for polypectomy versus a conservative approach.

Methods
A guidance development group comprising 28 members was established, including gastroenterologists, colorectal surgeons, elderly care physicians, anaesthetists, epidemiologists, nurse endoscopists, a general practitioner and patient representatives. Estimates on life expectancy stratified by age and comorbidity, polyp dwell time for differing polyp sizes, cancer sojourn time and polypectomy complication rates for comorbid/elderly patients both on and off antithrombotic medication were collated from various literature searches. A model was created to compare the risk of symptomatic malignancy in a patient’s lifetime against the risk of significant complications.

Results
Following a modified Delphi consensus process and after three rounds of voting, 33 recommendations were made within 10 domains (principles, diagnostic investigation, life expectancy, polyp and cancer natural history, polypectomy risks, management recommendations, follow-up, decision-making practicalities, training and education, future research). A table was created, summarising whether polypectomy or conservative management might be the favoured option for 40 clinical scenarios of patients with differing life expectancy, polyp sizes and use of antithrombotic medication.

Conclusions
This guidance provides a framework to facilitate more objective and informed decision-making, from which an individualised plan can be developed between the patient and their clinician.

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Guidance
Colorectal
BSG/ACPGBI guidance on the management of colorectal polyps in patients with limited life expectancy
clinical-resource/Management-of-colorectal-polyps-in-patients
This BSG and ACPGBI guidance aims to help clinicians and patients consider these risks to aid decision-making for polypectomy versus a conservative approach.

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Guidance
Clinical Resources Area
Suspected cancer: recognition and referral
clinical-resource/Suspected-cancer-recognition-and-referral
This guideline covers identifying children, young people and adults with symptoms that could be caused by cancer.