Overview
This guideline covers identifying children, young people and adults with symptoms that could be caused by cancer. It outlines appropriate investigations in primary care, and selection of people to refer for a specialist opinion. It aims to help people understand what to expect if they have symptoms that may suggest cancer.
We have used the terms 'men' and 'women' in some recommendations on gender-related cancers, but they also apply to people who have changed or are in the process of changing gender, and who retain the relevant organs.
Last reviewed: 1st May 2025
Please find below a summary table showing the key changes made to the recommendations, following stakeholder feedback:
| Old | New | |
| Oesophageal | 1.2.1 Offer urgent, direct access upper gastrointestinal endoscopy (to be done within 2 weeks) to assess for oesophageal cancer in people:
| 1.2.1 Refer people using a suspected cancer pathway referral for oesophageal cancer if they:
|
| Stomach | 1.2.7 Offer urgent, direct access upper gastrointestinal endoscopy (to be done within 2 weeks) to assess for stomach cancer in people:
| 1.2.7 Refer people using a suspected cancer pathway referral to assess for stomach cancer if they:
|
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Guidance
BSG, Association of Upper Gastrointestinal Surgery of Great Britain and Ireland & Royal College of Pathologists Delphi consensus guidance on biopsy sampling during upper GI endoscopy in adult patients
clinical-resource/BSG-AUGIS-RCPath-Delphi-consensus-guidance
These guidance statements represent a practical approach to tissue sampling in the upper gastrointestinal tract during endoscopy in adult patients.
UK & Ireland National Hepato-Pancreatobiliary (HPB) Nurses Audit
clinical-resource/UK-Ireland-National-HPB-Nurses-Audit
This audit exploring the practice and experiences of hepato-pancreato-biliary (HPB) nurses in the UK and Ireland would not have been possible without the support and collaboration of several individua