Guidelines for the Management of Gastroenteropancreatic Neuroendocrine (Including Carcinoid) Tumours

A multidisciplinary group compiled these guidelines for the clinical committees of the British Society of Gastroenterology, the Society for Endocrinology, the Association of Surgeons of Great Britain and Ireland, as well as its Surgical Specialty Associations, and the United Kingdom Neuroendocrine Tumour Group (UKNET). Over the past few years there have been advances in the management of NETs, which have included clearer characterisation, more specific and therapeutically relevant diagnosis, and improved treatments. However, there are few randomised trials in the field and the disease is uncommon; hence all evidence must be considered weak in comparison with other commoner cancers. It is our unanimous view that multidisciplinary teams at referral centres should give guidance on the definitive management of patients with gastroenteric and pancreatic NETs with representation that should normally include gastroenterologists, surgeons, oncologists, endocrinologists, radiologists, nuclear medicine specialists, and histopathologists. The working party that produced these guidelines included specialists from these various disciplines contributing to the management of gastrointestinal NETs. The purpose of these guidelines is to identify and inform the key decisions to be made in the management of gastroenteropancreatic NETs, including carcinoid tumours. The guidelines are not intended to be a rigid protocol but to form a basis upon which to aim for improved standards in the quality of treatment given to affected patients.