The Gut Microbiota for Health Expert Panel represents a group of multi-disciplinary members (including primary and secondary care clinicians, microbiologists, dietitians and research scientists) with expertise and interest in the gut microbiota and its role in health and disease. The Group is under the auspices of the British Society of Gastroenterology Research Committee.
The group was formed in 2013 and now includes over 50 members who meet twice a year, arrange meetings and workshops on key topics related to the microbiota and publish articles in high impact journals, as well as writing articles to enhance understanding with the public. As the Group has grown, it is now organised into Special Interest Groups (SIGs) but maintains the over-arching meetings to ensure continuity and sharing of expertise and interest.
The GMfH panel has achieved the following:
- Major contribution to BSG and HIS guidelines for FMT treatment for C diff
- Publication of a systematic review and meta-analysis of the efficacy of FMT for the treatment of recurrent and refractory C diff infection
- In conjunction with Guts UK, publication of a leaflet for the general public explaining about gut microbiome testing
- Publication of an article for the general public, explaining the importance of the gut microbiota for health.
- Publication of a highly cited scientific review on current knowledge about the gut microbiota in relation to gut disorders: metabolic syndrome and obesity-related disease, liver disease, IBD and colorectal cancer
- Contributions to BSG Research Workshops
- The Microbiome, Dysbiosis and GI disease. 11 April 2014
- Faecal Microbiota Transplantation: Bench, Bedside, Courtroom? 11 September 2015
The goals of the group are: to increase awareness and understanding among clinicians of the gut microbiota and its impact on health; to be a ‘go-to’ address for clinicians (GPs, gastroenterologists, nurses and allied health professionals) for defining what is currently reliably known in this field; and to drive scientific and academic interest in the gut microbiota primarily in gastrointestinal and liver disease – although our SIGs also cover nutrition, the gut-brain axis and infectious disease. Our website lists links to up-to-date papers selected by the SIG as being particularly relevant and topical. Each SIG will take turns to post articles here with news of developments in this rapidly evolving field of biology.
In particular, the group aims to:
- To map the science and reach consensus on what is known and what is not yet known
- To develop guidelines to promote good practice
- To draft consensus statements on areas of interest for UK GPs
- To identify gaps in knowledge and research foci
- To identify research and development areas in this field that would advance understanding and lead to patient benefit
The BSG committee on the Gut Microbiota for Health (GMfH) has now entered its seventh year and it is with great pleasure that I write this update. After its launch in 2013, the panel has continued to grow and make impacts in the area of gut microbiome research and outreach. One of the committee’s aims is to maximise the message on the importance of the gut microbiome in clinical settings and to provide information based on the best available evidence in forms that meet the needs of all levels of clinical service. To meet this aim we are actively recruiting clinical practitioners from primary care, nursing and trainees, to understand how we can help support better understanding and fill knowledge gaps. Moreover, we are trying to expand our understanding in areas that we feel are currently not as well served, for example the paediatric gut and its development, drug metabolism and the gut microbiota, novel treatments for gut disorders and the gut-liver axis.
A notable success for the committee was the publication of a set of national guidelines, written and driven by a significant set of members from the GMfH committee. The guidelines dealt with Faecal Microbiota Transplantation (FMT) for Clostridiodes difficile associated infections. The comprehensive guidelines were published in the peer-reviewed international journal Gut, as an open access paper. At the other end of the scale, in collaboration with the charity Guts UK, we will soon publish a general interest pamphlet on “testing your poo”. These two examples show that the GMfH committee is aiming to reach anyone interested in the role of the gut microbiota in health – clinicians, researchers, patients or general public. For the forthcoming year we will be engaging with primary health care workers, both nurses and GPs, to try and understand how we can help them to bring knowledge of the gut microbiota to this group of healthcare workers and onwards to the public.
On the expert side we recently held the 2nd BSG workshop on FMT at Birmingham University’s Medical School. Our host Prof. Tariq Iqbal and his colleagues hosted a morning session of talks that included regulatory as well as practical aspects of delivering an FMT, and an afternoon roundtable discussion looking at research in one session and the practicalities of FMT in another. A report of this workshop will soon be submitted to a major gastroenterology journal.
Going forward, the GMfH committee and its members are aiming to write more reviews of the topics on the microbiome in the developing paediatric gut, the gut liver axis, how drugs and the gut bacteria interact with one another. Some of these articles will be scientific reviews while others will be aimed at GPs. If you are interested in the panel, or have suggestions for future projects, please contact us.
Professor Julian Marchesi
Chair, Gut Microbiota for Health Expert Panel
A cross disciplinary education & interest group under the auspices of the British Society of Gastroenterology (BSG Research Committee)
- To help increase awareness and understanding among clinicians of the gut microbiota and its impact on health
- To be a ‘go-to’ address for UK clinicians (GPs, gastroenterologists, nurses and allied health professionals) for defining what is currently reliably known in this field
- To drive scientific and clinical interest in the gut microbiota in gastrointestinal and liver disease, including those with an autoimmune element
|Julian R. Marchesi (Chair; Cardiff University / Imperial College London)||Georgina Hold (University of Aberdeen)|
|Nigel Klein (Vice-Chair; University College London)||Darina Kohotouva (The Royal Marsden NHS Foundation Trust)|
|Secretariat: Linda Thomas (Society for Applied Microbiology)||Patricia Macnair (PCSG)|
|Tariq Iqbal (Chair Emeritus; University Hospital Birmingham)||Giles Major (University of Nottingham)|
|Ailsa Hart (Chair Emeritus; St Mark’s Hospital, Harrow)||Victoria McCune (PHE Birmingham)|
|Gregory Amos (NIBSC)||Pamela McDonald-Kuhne (Durham University)|
|Dagmar Alber (UCL Great Ormond Institute of Child Health)||John McLaughlin (University of Manchester)|
|James Alexander (Imperial College London)||Blair Merrick (Guys & St. Thomas’ NHS Foundation)|
|Ramesh Arasaradnam (University of Warwick)||Ben Mullish (Imperial College London)|
|Qasim Aziz (Royal London Hospital)||Ann Muls (The Royal Marsden NHS Foundation Trust)|
|Mona Bajaj-Elliott (UCL Great Ormond Institute of Child Health)||Mohammed Nabil Quraishi (University of Birmingham)|
|Kelly Bicknell (Queen Alexandra Hospital, Portsmouth)||Arjan Narbad (Institute of Food Research, Norwich)|
|Matthew Brookes (The Royal Wolverhampton NHS Trust)||Sarah O’Brien (University of Liverpool)|
|Gemma Brown (BSG)||Vishal Patel (KCL Institute of Liver Studies)|
|Barry Campbell (University of Liverpool)||Ian Rowland (formerly University of Reading)|
|Simon Carding (Institute for Food Research, Norwich)||Jonathan Segal (Imperial College London)|
|Bernard Corfe (University of Sheffield)||Naveen Sharma (Heart of England NHS Foundation)|
|Jamie Dalrymple (PCSG)||Debbie Shawcross (King’s College London)|
|Ngozi Elumgo (Norfolk and Norwich University Hospitals)||Liz Sheridan (Poole Hospital NHS Foundation Trust)|
|Ellen Fallows (Montgomery House Surgery, Bicester)||Jonathan Sutton (Ysbyty Gwynedd, Bangor)|
|Andrew Flatt (Queen Alexandra Hospital, Portsmouth)||Jonathan Swann (Imperial College London)|
|Konstantinos Gerasimidis (University of Glasgow)||Kevin Whelan (King’s College London)|
|Rohma Ghani (Imperial College London)||Leila White (Lancashire Teaching Hospitals NHS Foundation Trust)|
|Simon Goldenberg (Guy’s & St Thomas’ NHS Foundation Trust)||Peter Whorwell (University of Manchester)|
|Richard Hansen (University of Glasgow)||Horace Williams (Imperial College London)|
|Julie Harrington (Guts UK)||Charlotte Woodhouse (Maidstone and Tunbridge Wells NHS Trust)|
|Dean Harris (Swansea University)||Manuela Volta (Guts UK)|
|Peter Hawkey (University of Birmingham)|