The NIHR HTA funded Metric study (MR Enterography or ulTRasound In Crohn’s disease; “Diagnostic accuracy for the extent and activity of newly diagnosed and relapsed Crohn’s disease: a multicentre prospective comparison of magnetic resonance enterography and small bowel ultrasound compared to a reference standard in those aged 16 and over”) has closed to recruitment; data collection and analysis are underway.

The research team, led by Prof Stuart Taylor and Dr Andrew Plumb, were successful in securing £358,183 funding from the HTA for an add on study (MRI enterography as a predictor of disabling disease in newly diagnosed Crohn's disease) to develop a prognostic model for future disabling disease in those newly diagnosed with Crohn's disease. In particular, the group will investigate whether findings on MR enterography at diagnosis are predictive of a worse long-term outcome, over and above existing prognostic markers.

Co-investigators: Ailsa Hart, Andrew Plumb, Gauraang Bhatnagar, Nicola Muirhead, John Hamlin, Stuart Bloom, Susan Mallett, Ilan Jacobs, Susan Tebbs, Simon Travis, Stephen Morris, Steve Halligan.