First published on 06 Mar 2020
Trial name: Beta blockers Or Placebo for Primary Prophylaxis of oesophageal varices in cirrhosis (BOPPP). A triple blinded, multi-centre, clinical- and cost-effectiveness randomised controlled trial. Summary BOPPP is an NIHR HTA funded multi-centre trial to examine the efficacy using the […]
First published on 06 Mar 2020
CALIBRE – Carvedilol versus variceal band ligation in primary prevention of variceal bleeding in liver cirrhosis. Trial Design A multicentre randomised controlled, open-label, self-evident two-arm trial with internal pilot. Aim To investigate the clinical and cost-effectiveness of carvedilol versus variceal band ligation in patients […]
First published on 06 Mar 2020
ASEPTIC (Primary Antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis) is an NIHR HTA funded multi-centre trial to examine the efficacy of primary prophylaxis using the narrow-spectrum antibiotic Co-Trimoxazole in patients with cirrhosis and ascites. We are still […]
First published on 03 May 2019
Dear Colleague, We would like to invite you to participate in a new clinical trial: “STATIC – STopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-label, Non-inferiority Trial”. This is a fully funded study undertaken through a […]
First published on 23 Oct 2018
PROFILE is an investigator-led trial which aims to assess whether stratifying patients with Crohn’s disease from diagnosis based on a blood-test prognostic biomarker can help improve outcomes and quality of life. Aside from the biomarker it will also answer the […]
First published on 06 Aug 2018
ASTIClite – Autologous Stem cell Transplantation In refractory Crohn’s disease – Low Intensity Therapy Evaluation The ASTIClite trial aims to assess whether stem cell transplantation, with a low intensity treatment regimen, can reduce the symptoms and activity of Crohn’s disease […]
First published on 13 Oct 2017
PRECISION-Panc is an ambitious programme of research that seeks to uncover the molecular profile of individual patients with pancreatic cancer, to learn more about the disease and to pave the way for patients entering clinical trials in a way that matches […]
First published on 11 Oct 2017
Despite huge progress in the outpatient management of ulcerative colitis, there are still around 2,500 admissions for acute severe UC in the UK every year. Our current standard initial therapy (intravenous corticosteroids) is based upon the landmark trial of Truelove […]
First published on 09 Oct 2017
Joint collaborations between members of the British Society of Gastrointestinal and Abdominal Radiology (BSGAR) and the BSG have led to recent grant success from the NIHR. Led by Prof Stuart Taylor and Dr Andrew Plumb, the team has been awarded £895,292 […]
First published on 06 Oct 2017
A phase 2, multi-centre, international therapeutic trial has been approved in the UK for patients with Wilson’s disease. The Royal Surrey County Hospital, Guildford and Queen Elizabeth Hospital, Birmingham are the two UK sites, both of which have begun recruiting. Please […]