ASEPTIC - Antibiotic SpontanEous PeritoniTIs Cirrhosis

Primary Antibiotic Prophylaxis using Cotrimoxazole to Prevent Spontaneous Bacterial Peritonitis in Cirrhosis

UK wide multi-centre study: BOPPP Trial

Funded by the NIHR: HTA Programme

Now recruiting: Trial of Faecal Microbiota Transplantation (FMT) in Cirrhosis (PROFIT-01)

The primary objective of this study will be to assess whether stabilising gut dysbiosis with FMT in patients with advanced cirrhosis is both feasible and safe.

Receipt of Curative Resection or Palliative Care for Hepato-pancreatico-biliary Tumours

The aim of this study is to map the management pathway including investigations, biliary decompression and surgery from presentation to 90-day outcome for patients with pancreatic or peri-ampullary cancers as well as those with malignant biliary obstruction.

Researchers awarded £2.3m grant for clinical trial on patients with liver cirrhosis and oesophageal varices

Clinical researchers to lead a NIHR funded multicentre clinical trial to research CALIBRE

Minimising Mortality from Alcoholic Hepatitis

The MRC Stratified Medicine application entitled ‘Minimising Mortality from Alcoholic Hepatitis’ will commence in April 2018 and will last for 5 years.

UK Clinical Trials Gateway - Researcher Engagement Survey

The UKCTG service has traditionally provided public and professional users with information on what it means to participate in a clinical trial.

BADENOMA recruitment target met 9 months early

Action Medical Research awards £100k for IBD research

Dr Matthias Zilbauer, of the University of Cambridge, has been awarded £100k for a project aiming to find a way to predict how a child’s condition is likely to progress if they are diagnosed with IBD – whether the child’s symptoms are likely to be mild and require minimal treatment, or more severe, needing more intensive treatment

Three new clinical trials - personalising treatment in pancreatic cancer

PRECISION-Panc is an ambitious programme of research that seeks to uncover the molecular profile of individual patients with pancreatic cancer.

IASO trial of anakinra for acute severe ulcerative colitis

Despite huge progress in the outpatient management of ulcerative colitis, there are still around 2,500 admissions for acute severe UC in the UK every year.

METRIC Study closed for recruitment - add-on study funded

The research team were successful in securing £358,183 funding from the HTA for an add on study

Crohn's Disease trial funding success: cine MRI

Joint collaborations between members of the British Society of Gastrointestinal and Abdominal Radiology (BSGAR) and the BSG have led to recent grant success from the NIHR

NIHR Study Support Service Route Map

Planning to deliver a study in the NHS?

New HRA approval leaflet

The Health Research Authority (HRA) has published a new brief leaflet setting out high level information about the HRA Approval process.

New Wilson Disease trial recruiting now

A phase 2, multi-centre, international therapeutic trial has been approved in the UK for patients with Wilson's disease.

Registered Clinical Trials Units

The UK Clinical Research Collaboration (UKCRC) Registered CTU Network is a network of academic clinical trials units (CTUs) that have been assessed by an international panel of experts in clinical trials research.

Can aspirin stop cancer?

The world’s largest ever clinical trial looking at whether taking aspirin every day stops some of the most common cancers coming back launched on 22 October 2015.

Join the PANTS Study!

Inclusion of patients receiving Biosimilar Infliximab - Remsima™ & Inflectra™

HCV clinical trial and tissue biobank

HCV Research UK is a national cohort of over 11,000 patients enrolled between 2012 and 2014 from 60 centres within the UK with evidence of hepatitis C virus infection.