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Clinical Trials

STATIC Clinical Trial

First published on 03 May 2019

Dear Colleague, We would like to invite you to participate in a new clinical trial: “STATIC – STopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-label, Non-inferiority Trial”. This is a fully funded study undertaken through a […]

Clinical Trials

PROFILE Trial

First published on 23 Oct 2018

PROFILE is an investigator-led trial which aims to assess whether stratifying patients with Crohn’s disease from diagnosis based on a blood-test prognostic biomarker can help improve outcomes and quality of life. Aside from the biomarker it will also answer the […]

Clinical Trials

ASTIClite trial

First published on 06 Aug 2018

ASTIClite – Autologous Stem cell Transplantation In refractory Crohn’s disease – Low Intensity Therapy Evaluation The ASTIClite trial aims to assess whether stem cell transplantation, with a low intensity treatment regimen, can reduce the symptoms and activity of Crohn’s disease […]

Clinical Trials

IASO trial of anakinra for acute severe ulcerative colitis

First published on 11 Oct 2017

Despite huge progress in the outpatient management of ulcerative colitis, there are still around 2,500 admissions for acute severe UC in the UK every year. Our current standard initial therapy (intravenous corticosteroids) is based upon the landmark trial of Truelove […]

Clinical Trials

Crohn’s Disease trial funding success: cine MRI

First published on 09 Oct 2017

Joint collaborations between members of the British Society of Gastrointestinal and Abdominal Radiology (BSGAR) and the BSG have led to recent grant success from the NIHR. Led by Prof Stuart Taylor and Dr Andrew Plumb, the team has been awarded £895,292 […]