Research

Crohn’s and Colitis UK Research Awards 2018

Friday, 26 May 2017 13:22

Applications are invited for grants to be awarded in 2018 by Crohn's and Colitis UK. Research Projects may be directed towards:

  1. Medical - any aspect of Inflammatory Bowel Disease relevant to a better understanding of the causes or mechanisms of IBD or better treatment for IBD patients.
  2. Living with IBD - any aspect of the social and psychological impact of Inflammatory Bowel Disease including research into ways of helping patients and their families to live with IBD.
  3. Health Services - research with the potential to improve the services provided to the UK's IBD community and to drive up standards of care for patients with IBD.

Funding for any one project is normally subject to a maximum of £120,000 over a period of up to three years. Applications for funding of pilot studies are also encouraged.

Closing date for applications is 4pm on Friday, 22nd September 2017.

An Application Form and Information for Applicants can be downloaded from www.crohnsandcolitis.org.uk or contact us at This e-mail address is being protected from spambots. You need JavaScript enabled to view it or on 01727 734 468.

Bowel & Cancer Research - Funding Research

Wednesday, 19 April 2017 14:12

Call for proposals - EU applicants only

Bowel & Cancer Research is seeking proposals to support PhD students of up to £75,000 over 3 years. A minimum of three awards will be made in November 2017.

Bowel & Cancer Research funds translational research pertaining to diseases of the gastrointestinal tract. For this round, funding for one studentship will be restricted to a project to explore key genes for Ehlers Danlos Syndrome Hypermoblity Type (EDS-HT) and IBS.

Support will be given to:

  • New ideas in therapeutics, diagnostics or devices
  • Experimental medicine; studying human disease in human tissue
  • Trials; outcomes research

In general the charity does not fund work using experimental animals.

Because of the very strong link between B&CR and the National Bowel Research Centre, preference will be given to those applications that make some direct use of the facilities of the Centre or demonstrate a strong collaborative approach.

There is a one stage application process.
Application forms can be downloaded from: http://www.bowelcancerresearch.org/about-us/funding-research/
Applications should be returned by 5pm on Friday June 2nd
Final decisions on funding will be made in November
For queries relating to the programme contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it

CLDF £10,000 Grants Programme

Tuesday, 11 April 2017 10:06

Children’s Liver Disease Foundation (CLDF) are funding research grants with an overall aim of encouraging research in liver disease in children and young people. They aim to support preliminary research that will contribute significantly to a subsequent larger research grant proposal. Aside from the need to address liver disease in children, there are no restrictions on the scope of projects, which may focus on gaining insights into the causes of liver disease or improving diagnosis, management and longer-term outcomes. Awards can include basic, translational, laboratory, clinical or a social science focus. They can be used to pump prime a new project or support an ongoing project. Projects may be stand-alone or linked to one or more existing studies. Submissions are invited for awards up to a maximum of £10,000; they aim to award a number of grants. Further details are available on the small grants page. Applications are due no later than 5pm Friday 30th June 2017.

NIHR HTA Researcher-led calls 17/41 and 17/42

Tuesday, 11 April 2017 09:42

HTA 17/41 (expression of interest, evidence synthesis) and HTA 17/42 (researcher-led, expression of interest to full proposal) have been advertised. The application deadline for both calls is 1pm on 9 August 2017. Information and guidance are available on the linked pages of the NIHR website.

NIHR HTA 17/14 - Zoledronic acid to reduce fractures in patients with alcoholic liver disease

Monday, 03 April 2017 08:59

The HTA seeks to answer the question "Does administration of zoledronic acid to patients admitted to hospital with alcoholic liver disease (ALD) reduce the incidence of fractures and is it cost effective?" ALD accounts for 8% of all NHS medical admissions. Bone mineral density in ALD is reduced significantly. Fractures are globally four times as common in chronic alcoholics compared to age-matched controls; alcohol also increases the time to heal bone fractures and increases the risk of healing complications. The pathogenesis of the bone changes seen in alcohol abuse is still poorly understood so it is unclear if accepted treatments for osteoporosis will also work in the same way or as well in this patient group.

Zoledronic acid is a long acting intravenous bisphosphonate which reduces the risk of resulting fractures by 60% following a single administration in patients with osteoporosis. It is the only therapeutic agent used in the treatment of osteoporosis that has been shown to reduce mortality and it currently costs £170-250 for a single infusion. Patients with ALD are often poorly compliant with oral medication. A single intravenous infusion of zoledronic acid in those patients admitted with ALD and found to have increased risk of fractures offers the opportunity to improve bone density, reduce fracture incidence and perhaps improve mortality over the subsequent two years. This treatment may therefore help reduce the double financial burden brought to the NHS by patients with both ALD and osteoporosis.

If you're interested in learning more about this commissioned call, please download the file and its associated guidance. The deadline for applications is 1pm on 3 August 2017. A webinar will be held on Thursday 8 June 2017, at 14:30 - 16:00 (at the latest) to support applications to this funding opportunity. Please complete and submit this form to register your interest in attending. Applications will be considered by the HTA Funding Board at its meeting in September 2017. IMPORTANT: Investigators who submit applications that are shortlisted will be given a minimum of eight weeks to submit a full proposal. The full proposal will be considered at the Funding Board in January 2018.

NIHR HTA 17/33 - Management of diarrhoea in patients with stable ulcerative colitis

Friday, 31 March 2017 10:58

The HTA is looking for applicants to address the research question "Which intervention strategy is most effective, and most acceptable to patients, in the treatment of diarrhoea associated with stable ulcerative colitis?" The treatment strategy would utilise pharmacological and/or dietary interventions to manage diarrhoea in adult patients with stable ulcerative colitis who have at least some evidence of disease activity and who have diarrhoea which affects their quality of life. Further details are in the commissioning brief and guidance notes. This call responds to the IBD PSP's top 10 research priorities 3 and 6. Additional information to support applicants is available from the funding and support listing for this call. The deadline for applications is 1pm, 28 September 2017.

NIHR HTA 17/32 - Variceal bleeding in people with small oesophageal varices

Friday, 31 March 2017 10:46

The HTA is looking for applicants to answer the research questions "Do non-selective beta-blockers delay the onset or reduce the subsequent occurrence of variceal bleeding? Is their use cost effective?". This commissioned research call is based on BSG 2015 guidelines and NICE 2016 guidelines, both of which recognise that the current evidence for the use of nonsteroidal beta blockers as primary prevention is weak. Full details are in the commissioning brief and guidance notes. Additional information to support applicants is available from the funding and support listing. The deadline for applications is 1pm on 28 September 2017.

€100,000 for future scientific research project: Application for UEG Research Prize 2017 is now open!

Wednesday, 29 March 2017 12:42

The annual Research Prize is awarded for excellence in basic science, translational or clinical research. UEG support a future scientific research project from early stage to successful conclusion. The recipient must be able to demonstrate that their previous work has had an impact in its field and its quality is recognised internationally.

Application is open until May 12, 2017

MRC Clinical Research Training Fellowship Pre Doctoral (CRTF) opportunity

Thursday, 16 February 2017 15:54

The CRTF supports clinically active professionals within the UK to undertake a higher research degree. The scheme can also provide post-doctoral funding for applicants who achieved their PhD more than five years ago but who have not been research active since due to clinical training commitments. Further details can be found on the CRTF page and the deadlines page. Closing date: 06 Sep 2017.

MRC Biomedical Catalyst Developmental Pathway Funding Scheme

Thursday, 16 February 2017 15:43

DPFS supports the translation of fundamental discoveries toward benefits to human health. It funds the pre-clinical development and early clinical testing of novel therapeutics, devices and diagnostics, including “repurposing” of existing therapies. DPFS is an ongoing scheme, with outline deadlines every 4 months. The next two deadlines for outline proposals are

  • 4pm on 26 July 2017 (opens 15 June)
  • 4pm on 29 November 2017 (opens 20 October)
  •  

    The following activities are eligible for support:

  • Developing candidate therapeutic entities (e.g. drug discovery)
  • Pre-clinical testing of novel therapeutic entities
  • Early-phase clinical studies of novel therapeutic entities (phases 1 and 2)
  • “Repurposing” clinical studies – using existing therapies for new indications
  • Developing and testing novel devices
  • Developing and testing diagnostics (including biomarker validation)
  •  

    More information on remit, eligibility and application process are on the call page. Further details, including the deadlines for the next four calls, can be found on the submission deadlines page for the scheme.

    NIHR Programme Grants for Applied Research - Invitation for Applications

    Monday, 13 February 2017 16:47

    The NIHR Programme Grants for Applied Research programme invites Stage 1 research proposals to develop individual programmes. Research funded through a Programme Grant typically consists of an interrelated group of high quality projects focused on a coherent theme and hence require multidisciplinary approaches, including clinical, health economics, statistics, qualitative and behavioural sciences, to ensure that research objectives can be met. The amount awarded and the length of the funding period will depend on the nature of the proposed work, in particular whether or not the proposal includes a substantial powered trial. More details and how to apply can be accessed on the NIHR website. Competition 24 opens 1 June 2017 and closes at 1pm on 26 July 2017.

    NIHR Programme Development Grants

    Monday, 13 February 2017 16:39

    Programme Development Grants are designed to increase the rate and number of successful applications for a full Programme Grant. Competition 19 opens 25 May and closes at 1pm on 19 July 2017. Individual awards are for a maximum of £100k over a period of six to eighteen months. The amount of funding awarded is determined by the scale and nature of the research activity to be conducted. Details of the funding stream and the competition process are available from the NIHR website.

    Kenneth Rainin Foundation Funding Calendar

    Friday, 25 November 2016 15:01

    The Rainin Foundation believes that providing early support for innovative ideas can lead to improvements in preventing, diagnosing and treating Inflammatory Bowel Disease. Find out more about the Foundation and view their grant awards calendar.

    HTA researcher-led funding opportunities

    Tuesday, 02 August 2016 09:01

    The researcher-led workstream welcomes proposals on topics or research questions identified by researchers within the programme’s remit. The HTA can verify this for you if you complete and submit a remit check form. The deadlines for the next rounds are Wednesday 9 August 2017 and Tuesday 5 December 2017. Details can be found on the HTA website.

    The Kenneth Rainin Foundation - Innovator Awards

    Tuesday, 26 July 2016 15:26

    The Kenneth Rainin Foundation supports research that is potentially transformative to diagnosing, treating and curing Inflammatory Bowel Disease. The Innovator Awards program provides $100,000 grants for one-year research projects, which due to their ground-breaking nature, may not be suitable for funding from more traditional sources. To date, they have funded projects in the following areas:

    • Bioengineering
    • Diet and Nutrition
    • Epithelial Cell/Molecular Biology
    • Fecal Microbiota Transplant
    • Immunity and Inflammation
    • Microbiome
    • Therapeutic Development and Delivery

    If you are submitting a clinical research proposal, they encourage you to include basic scientific methodologies to examine the underlying mechanisms of the proposed intervention/treatment.

    Funding criteria include:

    • Innovation
    • Scientific merit
    • Strong evidence of collaboration
    • Investigator capability to execute project

    Researchers from any scientific discipline at non-profit research institutions worldwide are eligible for funding. Typically, the researchers they fund hold advanced degrees (MD, PhD or the equivalent) and academic positions at universities, medical centers or research institutions. Innovator Awards may have only one principal investigator, and funding is awarded to their home institution; however, additional investigators may be listed as co-investigators.

    Letter of Inquiry Deadline: January 15 – February 15, annually

    Further Information

    The Haemochromatosis Society Grants

    Thursday, 21 July 2016 08:22

    The Society works with the scientific community to support research into genetic haemochromatosis, and provides grants to tackle basic scientific, treatment or social issues that affect patients with haemochromatosis.

    Grant proposals are accepted at any time from researchers working in recognised institutions in the UK. Suitable applications progress to peer-review and a decision as to whether to fund a project is made at the earliest possible quarterly board meeting.

    Projects that may improve the rates of diagnosis and lower the average age of diagnosis of genetic haemochromatosis are welcome.

    Scientific research into iron overload and its treatment is ongoing worldwide. The society has a small research budget, which the trustees apply after consulting our scientific advisers, to support research in the UK.

    Further Information

    The American Society of Colon and Rectal Surgeons (ASCRS) Limited Project Grant (LPG)

    Tuesday, 24 May 2016 10:24

    Purpose

    To provide the investigator with the opportunity to pursue research interests, specifically germane to the field of colon and rectal surgery. It is anticipated that successful research projects, initially funded through the Research Foundation’s LPG mechanism, will ultimately secure funding from other national funding agencies.

    Amount
    Up to 50,000USD/year
    Application Deadlines: March 1st and October 1st
    Review/Notification Date: Summer/Fall (March applicants) or Winter/Spring (October applicants)

    Further Information / Apply

    MRC Supporting new researchers towards independence

    Thursday, 28 April 2016 14:09

    To support early career researchers the MRC has increased the flexibility of its funding schemes available to post-doc researchers along with providing clearer guidance. Recognising that speed of progression can be affected by factors unrelated to an individual’s scientific potential, the MRC have removed time-bound eligibility criteria from New Investigator Research Grants.

    Further Guidance

    MRC Regenerative Medicine Research - New Funding Approach

    Thursday, 28 April 2016 13:56

    MRC has recently made some changes to the way regenerative medicine research is funded.

    The Regenerative Medicine Research Committee will now focus funding into Confidence in Concept projects, spreading its £2m allocation over ten or so projects.

    Further Guidance

    MRC Flexible Funding

    Thursday, 28 April 2016 13:31

    MRC fellowships are open to individuals returning to research following a career break.

    Applicants should make clear any substantive periods of absence from research within their application. Details of career breaks or flexible working will only be used to make appropriate adjustments when assessing an individual’s track record, productivity and career progression.

    Further Details

    NIHR Invention for Innovation Programme

    Tuesday, 12 April 2016 11:15

    Invention for Innovation (i4i) is a translational funding scheme to advance healthcare technologies and interventions for increased patient benefit in areas of existing or emerging clinical need. i4i supports collaborative research and development projects that have demonstrated proof-of-principle and have a clear pathway towards adoption and commercialisation. The expected output is an advanced or clinically validated prototype medical device, technology or intervention. The aim is to de-risk projects and make them attractive to follow-on funders and investors.

    There are two funding streams, Product Development awards and Challenge awards, which comprise early to late stage product development, including first-in-man and clinical feasibility studies and pivotal clinical studies to evaluate the safety and effectiveness for the intended use. The ultimate aim is to get products or services to a position where they can enter and be used within the NHS. Details of the application deadlines and more are available on the i41 site.

    National Cancer Research Institute (NCRI) Advisory Group

    Friday, 08 April 2016 15:25

    The NCRI Advisory Groups offer specialist advice and peer review for trial proposals or ideas in the areas of Molecular Biomarkers, Imaging, and Screening Prevention & Early Diagnosis (SPED). The Advisory Groups are 'open for business' and encourage you to get in touch with your trial ideas.

    Find out more here.

    Broad Medical Research Program at CCFA (BMRP-CCFA)

    Friday, 08 April 2016 13:03

    Crohn’s & Colitis Foundation of America recognises the importance of conducting innovative research that will lead to improvements in the prevention, diagnosis or therapy of Crohn’s disease or ulcerative colitis. CCFA funds innovative, clinically relevant research projects that will have the potential to impact the lives of patients with inflammatory bowel diseases. If you have an idea for an exploratory pilot research project, please consider applying for a grant from BMRP-CCFA. This is an investigator- friendly process with a three page Letter of Interest with a rolling deadline open to any nationality and rapid turnaround for decisions. BMRP-CCFA aims to help persons with inflammatory bowel diseases (IBD) by stimulating innovative, early stage research that opens new avenues for the diagnosis, therapy and prevention of these diseases. BMRP-CCFA is a great mechanism to fund innovative ideas that are clinically relevant and can lead to rapid change in the care of patients with inflammatory bowel diseases. Interested parties can find further information about the program and the projects it seeks to fund.

    NIHR Research Design Service

    Friday, 08 April 2016 12:58

    The NIHR Research Design Service (RDS) network helps researchers prepare proposals for submission to NIHR and other national, peer-reviewed funding competitions for applied health or social care research, by providing expert advice on research design and methodology. RDS advisers in bases across England offer a unique breadth of experience and a proven track record in improving research applications. Advice is confidential and free of charge. For more information, visit the Research Design Service website.

    The Crohn's in Childhood Research Association Bursaries

    Thursday, 07 April 2016 15:22

    Bursary grants of up to £400 (up to a total amount of £5,000pa) to enable UK based young doctors still in training/nurses/final year medical students and similar persons with an interest in the area of Crohn's and colitis (IBD) to support attendance at national, international scientific/educational congresses and if considered appropriate IBD related training courses. Also a £1000 annual bursary for travel/registration at national and international meetings for doctors in training to become paediatric gastroenterologists.

    Application forms and further information can be obtained from the CICRA website: http://www.cicra.org/what-we-do/research/grant-applications