Research

NOW OPEN! Core-BSPGHAN Grant Round 2017 Deadline May 1st 2017

Thursday, 09 March 2017 10:08

Core and BSPGHAN are co-funding a scheme to provide financial support for the collection of pilot or proof-of-concept data that will enable a high-quality competitive application to be made subsequently to a research council or other large funder. Applications are invited from established investigators planning research studies on any topic within paediatric gastroenterology, hepatology and nutrition. We aim to fund 2 projects with a maximum budget of £35,000 per project and particularly welcome applications in nutrition, obesity and the microbiome. Further details and the application form can be found below.

Two Clinical Research Fellowships

Friday, 03 March 2017 11:44

Two fully funded Clinical Research Fellowships are being offered in Nottingham and London. The fellowships relate to the TRITON grant that was recently announced. More details can be found in this PDF and in the links to each location mentioned above. Interested parties need to apply directly via the university websites.

MRC Clinical Research Training Fellowship Pre Doctoral (CRTF) opportunity

Thursday, 16 February 2017 15:54

The CRTF supports clinically active professionals within the UK to undertake a higher research degree. The scheme can also provide post-doctoral funding for applicants who achieved their PhD more than five years ago but who have not been research active since due to clinical training commitments. Further details can be found on the CRTF page and the deadlines page. Closing date: 06 Sep 2017.

MRC Biomedical Catalyst Developmental Pathway Funding Scheme

Thursday, 16 February 2017 15:43

DPFS supports the translation of fundamental discoveries toward benefits to human health. It funds the pre-clinical development and early clinical testing of novel therapeutics, devices and diagnostics, including “repurposing” of existing therapies. DPFS is an ongoing scheme, with outline deadlines every 4 months. The next two deadlines for outline proposals are

  • 4pm on 29 March 2017
  • 4pm on 26 July 2017
  • The following activities are eligible for support:

  • Developing candidate therapeutic entities (e.g. drug discovery)
  • Pre-clinical testing of novel therapeutic entities
  • Early-phase clinical studies of novel therapeutic entities (phases 1 and 2)
  • “Repurposing” clinical studies – using existing therapies for new indications
  • Developing and testing novel devices
  • Developing and testing diagnostics (including biomarker validation)
  • More information on remit, eligibility and application process are on the call page. Further details, including the deadlines for the next four calls, can be found on the submission deadlines page for the scheme.

    Four grant types available from MRC Molecular & Cellular Medicine Research Boards

    Wednesday, 15 February 2017 18:21

    You can apply to the Molecular & Cellular Medicine Board through the following grant schemes:

  • Research grant
  • Programme grant
  • New investigator research grant
  • Partnership grant
  • Closing date is 3 May 2017.

    MRC Senior Clinical Fellowship

    Wednesday, 15 February 2017 18:16

    The Senior Clinical Fellowship supports talented medically and other clinically qualified professionals, with an effective track record of internationally competitive independent research, to make the transition to research leadership. The application deadline is 4pm on 5 April 2017. More details are available from the SCF page. Applications across the full MRC remit are welcome.

    MRC Clinician Scientist Fellowship

    Wednesday, 15 February 2017 18:11

    Applications across the full MRC remit are welcome. Got to the relevant MRC call page and the Clinican Scientist Fellowship page for more details. The call deadline is 4pm on 5 April 2017.

    NIHR Programme Grants for Applied Research - Invitation for Applications

    Monday, 13 February 2017 16:47

    The NIHR Programme Grants for Applied Research programme invites Stage 1 research proposals to develop individual programmes. Research funded through a Programme Grant typically consists of an interrelated group of high quality projects focused on a coherent theme and hence require multidisciplinary approaches, including clinical, health economics, statistics, qualitative and behavioural sciences, to ensure that research objectives can be met. The amount awarded and the length of the funding period will depend on the nature of the proposed work, in particular whether or not the proposal includes a substantial powered trial. More details and how to apply can be accessed on the NIHR website. Competition 23 closes at 1pm on 29 March 2017; Competition 24 opens 1 June 2017 and closes at 1pm on 26 July 2017.

    NIHR Programme Development Grants

    Monday, 13 February 2017 16:39

    Programme Development Grants are designed to increase the rate and number of successful applications for a full Programme Grant. Competetion 18 opened 26 January and closes at 1pm on 22 March 2017. Competition 19 opens 25 May and closes at 1pm on 19 July 2017. Individual awards are for a maximum of £100k over a period of six to eighteen months. The amount of funding awarded is determined by the scale and nature of the research activity to be conducted. Details of the funding stream and the competition process are available from the NIHR website.

    forCrohn's Innovation Grant 2017

    Monday, 09 January 2017 12:08

    Background

    forCrohn's is the UK's only charity solely dedicated to Crohn’s disease. Their mission is to fund research that helps those with the condition today and contributes to finding a cure for Crohn's disease in the future whilst making more people in the UK aware of the disease and its symptoms. They fund £80,000-100,000 basic science and clinical research annually in various specialist institutions.

    Aim of the Innovation Grant

    The aim is to support gastroenterology healthcare professionals to find new ways to immediately improve the lives of patients with Crohn's disease.

    Funding

    forCrohn's new innovation grant will be used to fund projects that demonstrate a clear and immediate benefit for Crohn's disease patients. Up to £10,000 will be awarded to successful applicants. The application process is open from 1 January 2017 - 13 March 2017.

    Criteria of grant

    All projects must meet the following criteria and will be judged against them:

    • An outcome which demonstrates a clear and immediate benefit for Crohn's patients
    • (Whilst it is appreciated that many projects may have a dual benefit for those with UC, the charity's main aim is focused on the output for Crohn's)
    • A short expected time between study and implementation
    • Robust assessment of outcomes
    • Potential to scale nationally for pilot projects

    For more information about the Innovation Grant and to download an application form, please go to http://bit.ly/forcrohnsinnovation

     

    HTA 16/166 & 16/167 - Researcher-led open calls

    Friday, 16 December 2016 16:05

    HTA 16/167 (researcher-led, expression of interest to full) and HTA 16/166 (researcher-led, evidence synthesis full proposal) have been advertised. The application deadline for both calls is 1pm on 5 April 2017. Information and guidance are available on the NIHR website.

    NIHR PGFAR - Competition 23

    Monday, 28 November 2016 17:05

    Programme Grants aim to produce independent research findings that will have practical application for the benefit of patients and the NHS in the relatively near future. Programme Development Grants are a complementary scheme to allow investigators to undertake preparatory research that will position them to submit a competitive Programme Grant application. The deadline for submission of Stage 1 applications is 1pm 29 March 2017. Research funded through a Programme Grant typically consists of an interrelated group of high quality projects focused on a coherent theme. The projects will therefore require multidisciplinary approaches, including clinical, health economics, statistics, qualitative and behavioural sciences, to ensure that research objectives can be met. The amount awarded and the length of the funding period will depend on the nature of the proposed work, in particular whether or not the proposal includes a substantial powered trial. Programme Grants will now launch three Competitions per year, with Stage 1 opening for applications in February, June and October. Please see the call schedule on the PGFAR Calls and Competitions page for further details.

    NIHR HTA 16/162 - Low-dose antidepressants for the treatment of irritable bowel syndrome

    Monday, 28 November 2016 12:55

    There is some evidence for the clinical effectiveness of low-dose antidepressants in treating the symptoms of IBS. However, this comes from studies based primarily within secondary or tertiary care settings with low participation rates. There is uncertainty about whether these drugs are effective for people with IBS seen in primary care. Most people with IBS are treated in this setting, and may be different in a number of respects to those seen in secondary and tertiary care. Therefore, research on the relative short- and long-term benefits of low-dose TCAs and/or SSRIs in primary care populations would help guide treatment decisions. The Health Technology Assessment Programme therefore seeks to answer "What is the clinical and cost effectiveness of low-dose TCAs and/or SSRIs for the treatment of irritable bowel syndrome (IBS) in primary care?" Details of the commissioning call are available from the NIHR website, along with the guidance notes. The deadline for applications is 1pm on 6 April 2017.

    NIHR HTA 16/152 - Selective gut decontamination in critically ill children

    Monday, 28 November 2016 12:45

    In order to answer the research question "Is it feasible to conduct a study of selective gut decontamination in critically ill children in paediatric intensive care?", the Health Technology Assessment (HTA) programme is commissioning research into whether selective gut decontamination through oropharyngeal and gastric application of specific non-absorbable antibiotics to reduce/eradicate the presence of harmful microorganisms only, as opposed to using broad spectrum antibiotics that can disrupt the gut’s natural flora, can directly or indirectly reduce morbidity and mortality in children admitted to paediatric intensive care units. There is the risk of antibiotic resistance developing. Therefore, the Paediatric Intensive Care Society has highlighted that this is an important area for further research before such a strategy can be recommended. Given that this intervention is not currently used in UK PICUs, a feasibility and randomised pilot trial is proposed in the first instance to determine whether it will be possible to deliver a substantive trial. Potential applicants are also directed to the guidance notes. Applications are due by 1pm on 6 April 2017.

    Kenneth Rainin Foundation Funding Calendar

    Friday, 25 November 2016 15:01

    The Rainin Foundation believes that providing early support for innovative ideas can lead to improvements in preventing, diagnosing and treating Inflammatory Bowel Disease. Find out more about the Foundation and view their grant awards calendar.

    Graham Bull prize in clinical science and Goulstonian Lectureship 2017

    Wednesday, 23 November 2016 13:07

    The Graham Bull prize was established in 1988 in honour of Sir Graham Bull, who was the first director of the Clinical Research Centre at Northwick Park. A trust for the Graham Bull prize was set up to provide money for young research workers under the age of 45 who feel that they have made a major contribution to clinical science.

    The prize as designed by the trust is specifically for an application and not for nomination of individuals. The work can cover a wide range of expertise, such as:

    • molecular and cellular biology
    • imaging technology
    • psychiatry
    • health sciences

    The award is open to RCP members and fellows who must apply for their own work to be considered. The sum of £1,000 is offered on a competitive basis each year.

    The winner of this prize will be invited to deliver the Goulstonian Lecture, an annual lecture endowed in 1635 by Mrs Ellen Goulston in memory of her husband, Dr Theodore Goulston FRCP.

    Researchers must be under the age of 45 on the application closing date (as per the terms of the original bequest), and must be a member or fellow of RCP London.

    Further information, including details of how to apply, may be found on the RCP website:

    Deadline for applications: Friday 31st March 2017

    NIHR Public Health Research Programme 16/121 - Healthy diet in early years

    Monday, 17 October 2016 09:04

    Background to commissioning brief

    Healthy dietary intake during the early years of life supports children to grow and develop physiologically and psychologically towards a healthy life, and is important in preventing and reducing obesity, as highlighted in the recently published government Childhood Obesity plan for action.

    Interventions which promote breastfeeding and that improve weaning and dietary quality in early years can reduce the risk of over-nutrition and chronic diseases in later life. Interventions designed to promote healthy diet and good nutrition in early childhood need to understand and address the factors influencing and determining children’s diets.

    Establishing healthy weaning practices and developing eating habits may cause concern for parents, with little information on the best approaches, and addressing problems. However, despite the increasing number of interventions and public health importance, results continue to be inconsistent and there is a lack of well - designed studies evaluating interventions for healthy diets in early years. Population level interventions are of interest.

    Deadline: 1pm, 25 April 2017

    Further Information

    Additional Documents

    HTA researcher-led funding opportunities

    Tuesday, 02 August 2016 09:01

    The researcher-led workstream welcomes proposals on topics or research questions identified by researchers within the programme’s remit. The HTA can verify this for you if you complete and submit a remit check form. The deadlines for the next rounds are Wednesday 30 November 2016, Wednesday 5 April 2017, Wednesday 9 August 2017, Tuesday 5 December 2017. Details can be found on the HTA website.

    2016 NIHR Clinical Lectureships (Medical)

    Friday, 29 July 2016 11:28

    The 2016 NIHR Clinical Lectureships (medical) opened on 1st March 2016 and will close on 31st March 2017.

    NIHR Clinical Lectureships (CLs) are specialty training posts that incorporate academic training. NIHR Clinical Lecturers (CLs) spend 50% of their time undertaking specialist clinical training and 50% undertaking research or educational research training.

    CLs are aimed at those who are advanced in their specialty training, have completed a research doctorate or equivalent and show outstanding potential for continuing a career in academic medicine. The duration of a CL is for a maximum of 4 years and it is expected that CLs will complete their specialty training during this period. Alongside clinical training, CLs will be able to further develop their academic skills and will be encouraged to apply for funding to support further Post-Doctoral or educational research training.

    There are currently two gastroenterology posts open, which you can view on the list below. The first is in Yorkshire & Humber, Sheffield the second in Wessex, Southampton.

    List of open posts

    Further Information

    You may also be interested in:

    The Kenneth Rainin Foundation - Innovator Awards

    Tuesday, 26 July 2016 15:26

    The Kenneth Rainin Foundation supports research that is potentially transformative to diagnosing, treating and curing Inflammatory Bowel Disease. The Innovator Awards program provides $100,000 grants for one-year research projects, which due to their ground-breaking nature, may not be suitable for funding from more traditional sources. To date, they have funded projects in the following areas:

    • Bioengineering
    • Diet and Nutrition
    • Epithelial Cell/Molecular Biology
    • Fecal Microbiota Transplant
    • Immunity and Inflammation
    • Microbiome
    • Therapeutic Development and Delivery

    If you are submitting a clinical research proposal, they encourage you to include basic scientific methodologies to examine the underlying mechanisms of the proposed intervention/treatment.

    Funding criteria include:

    • Innovation
    • Scientific merit
    • Strong evidence of collaboration
    • Investigator capability to execute project

    Researchers from any scientific discipline at non-profit research institutions worldwide are eligible for funding. Typically, the researchers they fund hold advanced degrees (MD, PhD or the equivalent) and academic positions at universities, medical centers or research institutions. Innovator Awards may have only one principal investigator, and funding is awarded to their home institution; however, additional investigators may be listed as co-investigators.

    Letter of Inquiry Deadline: January 15 – February 15, annually

    Further Information

    The Haemochromatosis Society Grants

    Thursday, 21 July 2016 08:22

    The Society works with the scientific community to support research into genetic haemochromatosis, and provides grants to tackle basic scientific, treatment or social issues that affect patients with haemochromatosis.

    Grant proposals are accepted at any time from researchers working in recognised institutions in the UK. Suitable applications progress to peer-review and a decision as to whether to fund a project is made at the earliest possible quarterly board meeting.

    Projects that may improve the rates of diagnosis and lower the average age of diagnosis of genetic haemochromatosis are welcome.

    Scientific research into iron overload and its treatment is ongoing worldwide. The society has a small research budget, which the trustees apply after consulting our scientific advisers, to support research in the UK.

    Further Information

    The Society for Surgery of the Alimentary Tract (SSAT) Career Development Award

    Friday, 17 June 2016 10:19

    This award for young faculty members is to assist in the establishment of investigators, basic or clinical, in digestive diseases.

    Eligibility Criteria

    • The supported research program can be focused on basic laboratory or rigorous clinical investigation.
    • The award is restricted to surgeons who have completed formal clinical and research training in general surgery and are within five years of their first faculty appointment in a department of surgery at a medical school accredited by the Liaison Committee on Medical Education in the United States or by the Committee for Accreditation of Canadian Medical Schools in Canada, or the equivalent national accrediting body for applicants from other countries.
    • A significant amount of time should be devoted to research to accomplish the investigator's goals. The Head of Department and Division of General Surgery must ensure that the applicant has the required protected time for research.
    • The SSAT award of $50,000USD per year for two years is a career development award and is meant to support young investigators who have not been funded by a National Institutes of Health R01 Award. In addition, if an investigator has received a similar type career development award from another organization such as the American College of Surgeons, American Surgical Association Foundation, etc., he/she will be ineligible for the SSAT Career Development Award. This is the applicant's responsibility to notify the SSAT of potential funding conflicts.
    • The award is not to diminish or replace the customary, expected compensation or benefits; nor is any portion of the award to be used for institutional indirect costs.
    • The recipient will present a progress report to the SSAT Annual Meeting during and immediately following the period of award.
    • It is expected that the recipient submit any abstracts deriving from his/her Career Development Award-funded research to the SSAT Annual Meeting for presentation consideration, as well as any manuscripts to the Journal of Gastrointestinal Surgery, the official journal of the SSAT, for publication consideration.

    Further Information

    The deadline for the 2017 award is January 13, 2017.

    The American Society of Colon and Rectal Surgeons (ASCRS) Limited Project Grant (LPG)

    Tuesday, 24 May 2016 10:24

    Purpose

    To provide the investigator with the opportunity to pursue research interests, specifically germane to the field of colon and rectal surgery. It is anticipated that successful research projects, initially funded through the Research Foundation’s LPG mechanism, will ultimately secure funding from other national funding agencies.

    Amount
    Up to 50,000USD/year
    Application Deadlines: March 1st and October 1st
    Review/Notification Date: Summer/Fall (March applicants) or Winter/Spring (October applicants)

    Further Information / Apply

    Health Education England (HEE) and NIHR Webinar

    Thursday, 05 May 2016 08:40

    HEE and NIHR hosted a webinar providing an overview of its Integrated Clinical Academic (ICA) Programme but also useful hints and tips for applying.

    It is a useful resource for those applying for Round 2 competitions for Clinical Doctoral Research Fellowships and Clinical Lectureships and Senior Clinical Lectureships.

    You’ll need to register first before watching the webinar.

    MRC Supporting new researchers towards independence

    Thursday, 28 April 2016 14:09

    To support early career researchers the MRC has increased the flexibility of its funding schemes available to post-doc researchers along with providing clearer guidance. Recognising that speed of progression can be affected by factors unrelated to an individual’s scientific potential, the MRC have removed time-bound eligibility criteria from New Investigator Research Grants.

    Further Guidance

    MRC Regenerative Medicine Research - New Funding Approach

    Thursday, 28 April 2016 13:56

    MRC has recently made some changes to the way regenerative medicine research is funded.

    The Regenerative Medicine Research Committee will now focus funding into Confidence in Concept projects, spreading its £2m allocation over ten or so projects.

    Further Guidance

    MRC Flexible Funding

    Thursday, 28 April 2016 13:31

    MRC fellowships are open to individuals returning to research following a career break.

    Applicants should make clear any substantive periods of absence from research within their application. Details of career breaks or flexible working will only be used to make appropriate adjustments when assessing an individual’s track record, productivity and career progression.

    Further Details

    NIHR Invention for Innovation Programme - 12th call for Product Development Awards

    Tuesday, 12 April 2016 11:15

    Invention for Innovation (i4i) is a translational funding scheme to advance healthcare technologies and interventions for increased patient benefit in areas of existing or emerging clinical need. Similarly, the Health Innovation Challenge Fund (HIC Fund), a partnership between the Department of Health and the Wellcome Trust, is also a translational funding scheme and complements the NIHR i4i Programme at a key translational gap.

    i4i supports collaborative research and development projects that have demonstrated proof-of-principle and have a clear pathway towards adoption and commercialisation. The expected output is an advanced or clinically validated prototype medical device, technology or intervention. The aim is to de-risk projects and make them attractive to follow-on funders and investors.

    There are two funding streams, Product Development awards and Challenge awards, which comprise early to late stage product development, including first-in-man and clinical feasibility studies and pivotal clinical studies to evaluate the safety and effectiveness for the intended use. The ultimate aim is to get products or services to a position where they can enter and be used within the NHS.

    National Cancer Research Institute (NCRI) Advisory Group

    Friday, 08 April 2016 15:25

    The NCRI Advisory Groups offer specialist advice and peer review for trial proposals or ideas in the areas of Molecular Biomarkers, Imaging, and Screening Prevention & Early Diagnosis (SPED). The Advisory Groups are 'open for business' and encourage you to get in touch with your trial ideas.

    Find out more here.

    CLDF Small Grants Programme

    Friday, 08 April 2016 13:28

    The trustees of Children’s Liver Disease Foundation (CLDF) will make available £20,000 per annum for a small grants research programme. Applications must be in line with CLDF's research strategy. The money will be distributed quarterly with a maximum of £5,000 being awarded in any one quarter. Applicants may apply for up to £5,000 in a quarter. Successful applicants will not be eligible to apply for a further year following an award being made. The trustees will look favourably on applications where the candidates can show that they can add value to the contribution made by CLDF. Those who can show matching funding from their institution or other sources will be regarded favourably. The next funding round is 1 October – 31 December followed by 1 January – 31 March. Please find information on applying for a CLDF Small Grant here.

    Broad Medical Research Program at CCFA (BMRP-CCFA)

    Friday, 08 April 2016 13:03

    Crohn’s & Colitis Foundation of America recognises the importance of conducting innovative research that will lead to improvements in the prevention, diagnosis or therapy of Crohn’s disease or ulcerative colitis. CCFA funds innovative, clinically relevant research projects that will have the potential to impact the lives of patients with inflammatory bowel diseases. If you have an idea for an exploratory pilot research project, please consider applying for a grant from BMRP-CCFA. This is an investigator- friendly process with a three page Letter of Interest with a rolling deadline open to any nationality and rapid turnaround for decisions. BMRP-CCFA aims to help persons with inflammatory bowel diseases (IBD) by stimulating innovative, early stage research that opens new avenues for the diagnosis, therapy and prevention of these diseases. BMRP-CCFA is a great mechanism to fund innovative ideas that are clinically relevant and can lead to rapid change in the care of patients with inflammatory bowel diseases. Interested parties can find further information about the program and the projects it seeks to fund.

    NIHR Research Design Service

    Friday, 08 April 2016 12:58

    The NIHR Research Design Service (RDS) network helps researchers prepare proposals for submission to NIHR and other national, peer-reviewed funding competitions for applied health or social care research, by providing expert advice on research design and methodology. RDS advisers in bases across England offer a unique breadth of experience and a proven track record in improving research applications. Advice is confidential and free of charge. For more information, visit the Research Design Service website.

    New research funding announced by MRC 15 February 2016

    Thursday, 07 April 2016 15:46

    The Medical Research Council (MRC) is accelerating innovative medical research with £23.2 million in new funding to take ground-breaking ideas from UK universities into industry and out to patients.

    The Crohn's in Childhood Research Association Bursaries

    Thursday, 07 April 2016 15:22

    Bursary grants of up to £400 (up to a total amount of £5,000pa) to enable UK based young doctors still in training/nurses/final year medical students and similar persons with an interest in the area of Crohn's and colitis (IBD) to support attendance at national, international scientific/educational congresses and if considered appropriate IBD related training courses. Also a £1000 annual bursary for travel/registration at national and international meetings for doctors in training to become paediatric gastroenterologists.

    Application forms and further information can be obtained from the CICRA website: http://www.cicra.org/what-we-do/research/grant-applications

    MRC Biochemical Catalyst: Developmental Pathway Funding Scheme

    Thursday, 07 April 2016 15:20

    The DPFS scheme is a key part of the MRC's Translational Research Strategy and supports the translation of fundamental discoveries toward benefits to human health. It funds the pre-clinical development and early clinical testing of novel therapeutics, devices and diagnostics, including “repurposing” of existing therapies. DPFS is an ongoing scheme, with outline deadlines every 4 months. The next three deadlines for outline proposals are 4pm on 29th March 2017, 26 July 2017 and 29 November 2017. Further details, including the deadlines for the next three calls, can be found on the submission deadlines page for the scheme.

    Please note that full submissions to DPFS are by invitation only; submission to the full call is contingent upon prior submission and shortlisting of an outline proposal. Further details are available from the MRC website.

    Pump prime funding for initial feasibility studies

    Thursday, 07 April 2016 15:17

    NIHR Enteric HTC aims to identify and address unmet clinical need in the diagnosis and management of disorders of the gastrointestinal tract and bowel function. The HTC seeks new ideas for medical device innovations and offers the opportunity to apply to NIHR Enteric HTC for pump prime funding for initial feasibility studies on potential new medical technologies within the field of digestive diseases and GI surgery.