Research News

New study to examine thre role of vitamin D in the progression of paediatric NAFLD

Monday, 26 November 2012 08:19

Children's Liver Disease FoundationChildren's Liver Disease Foundation (CLDF), the UK’s leading charity fighting childhood liver disease, is to fund a PhD student fellowship at the University of Surrey which will look at the role of vitamin D in the progression of paediatric non-alcoholic fatty liver disease (NAFLD), now recognised as the most common cause of childhood liver disease in the UK.

The £74,500 award will fund a three year study, to be led by Dr Bernadette Moore, a lecturer in molecular nutrition at the University, who will be working in collaboration with Kings College Hospital Paediatric Liver Clinic.

"We are thrilled that CLDF have agreed to fund this project which will enable us to find out more about a disease which is affecting increasing numbers of UK children," commented Dr Moore. "The incidence of paediatric NAFLD has risen sharply in past three decades, affecting an estimated 3–9% of all children and up to 70% of obese children."

"Whilst we know that people in the UK have low level vitamin D status during the winter due to the lack of sunlight, children with fatty liver disease have been shown to have particularly low levels and this deficiency is associated with more severe liver disease. This project will examine the diet and specific genes that can affect vitamin D levels in UK children with liver disease."

Publicly funded research to be free of charge to readers

Wednesday, 02 May 2012 11:31

David Willetts, Minister of State for Universities and Science, announced that the UK Government "will make publicly funded research accessible free of charge to readers. Giving people the right to roam freely over publicly funded research will usher in a new era of academic discovery and collaboration, and will put the UK at the forefront of open research." Download the article and read more about how Wikipedia's co-founder, Jimmy Wales, "will assist the Department for Business, Innovation and Skills and the UK Research Councils to develop new ways to store and distribute research data and articles."

Looking for research-interested surgeons

Friday, 27 January 2012 12:04

Are you a surgeon active in research?

The BSG is hoping to engage with the Royal College of Surgeons, the NIHR and NCRI on the GRIST project: Growing Recruitment in Surgical Trials. One of the aspects of this work is looking at how clinical trials profiles can be raised within surgical units. If you are a surgeon active in research, or would like to become active or involved in surgical research, please email This e-mail address is being protected from spambots. You need JavaScript enabled to view it with your contact details and a brief description of your experience and research interests.

Further information on clinical research in the UK (including local contacts for gastroenterology, hepatology and subspecialty interests) can be found under the Research area of the BSG’s website.

Update on HOT II Trial – Last call for volunteers

Wednesday, 18 January 2012 15:24

The HOT II Trial is looking for 5-10 additional volunteers who may be interested to take part, following a further extension of the accrual period, which needs to finish by the end of March 2012 in order for all volunteers to be treated by the end of the year. Please let Grace Sharp (HOT II Trial Coordinator; This e-mail address is being protected from spambots. You need JavaScript enabled to view it ) know of any potentially suitable volunteers amongst your patients AS SOON AS POSSIBLE.

For further information or to refer a patient, please see Clinical Trial Updates.

Page 9 of 11