Research News

Opportunities to influence health research in the UK with NIHR

Tuesday, 07 March 2017 09:25

NIHR research programme boards and panels select the most important research questions to commission, and make funding recommendations on project applications.

They are looking for additional expertise for the boards or panels of the following programmes:

  • Efficacy and Mechanism Evaluation (EME) Programme
  • NIHR Health Services and Delivery Research (HS&DR) Programme
  • NIHR Health Technology Assessment (HTA) Programme
  • NIHR Public Health Research (PHR) Programme

Applications close on 21 April 2017 at 1pm. Further details and information on how to apply are available on our website: http://www.nihr.ac.uk/about-us/advisory-group-opportunities/

There are also currently a number of opportunities for Chairs of their boards and panels: http://www.nihr.ac.uk/about-us/nihr-vacancies/

 

IASO trial of anakinra for acute severe ulcerative colitis

Thursday, 02 March 2017 16:52

Despite huge progress in the outpatient management of ulcerative colitis, there are still around 2,500 admissions for acute severe UC in the UK every year. Our current standard initial therapy (intravenous corticosteroids) is based upon the landmark trial of Truelove and Witt in the 1950s; advances since have been restricted to rescue therapy for those failing this initial care. Led by Tim Raine and Arthur Kaser in Cambridge, with a team of researchers from across the UK, the IASO trial will be a multicentre, randomised, double-blind, placebo-controlled trial to test the hypothesis that IL-1 blockade using anakinra, a safe and affordable antagonist of the IL-1 receptor, can improve outcomes when given as initial therapy in acute severe UC alongside corticosteroids. Funding for IASO has been provided by the NIHR and MRC through the EME programme, with additional funding from the Wellcome Trust and Swedish Orphan Biovitrum, totalling in all in excess of £1.6m. IASO will set this major clinical trial in the context of a detailed scientific study of the largest cohort of patients with acute severe UC ever assembled. Patient recruitment will begin in 2017, with final trial reporting expected in 2021/22.

UEG's basic science offerings

Wednesday, 01 March 2017 11:59

UEG sent a recent newsletter outlining what they offer basic scientists.

Infographic on the drug discovery process

Tuesday, 28 February 2017 10:47

Compoundchem.com is an interesting website full of infographics relating to the role of chemistry in daily life. For example, last week, graphics were posted on chemistry in films and the composition of the Oscar statuettes. If this isn't your thing, you might be interested in an infographic on the drug discovery process with some accompanying text.

Page 8 of 38