Research News

Gastroenterology-led TRIGGER trial of transfusion strategies for GI bleeding published in the Lancet

Wednesday, 15 July 2015 12:38

TRIGGER is a multicentre randomised pilot trial comparing red blood cell transfusion strategies for Acute Upper Gastrointestinal Bleeding (AUGIB). Through the examination of liberal and restrictive policies for transfusion, TRIGGER established that, with further research, the way AUGIB is treated in the UK could change significantly, benefitting patients and producing significant cost savings for the NHS.

This work directly followed on from the British Society of Gastroenterology (BSG)-supported UK national audit of GI bleeding, which was led by Kel Palmer and others. The trial was delivered through a successful collaboration within and between UK gastroenterology centres and other groups. Prof John McLaughlin, the BSG's Research Committee Chairman while the trial was being carried out, said "This fantastic piece of work shows the power of collaborative research. Hopefully the NIHR will support a follow-on study of restrictive transfusion for AUGIB, which has the potential to benefit individual patients and the NHS as a whole."

Outcome of the IBD Research Priority-Setting Partnership

Friday, 27 February 2015 18:08

After an incubation period of several years, the IBD PSP has completed the exercise to determine and rank research priorities in IBD. The PSP consisted of patients, carers and clinicians (surgeons, nurses, dieticians and medical gastroenterologists) and worked to an iterative process designed and supervised by the James Lind Alliance. More than 1600 suggestions were made, which through a process of elimination (not research uncertainties, duplication of ideas from multiple sources, not treatment-related etc) were whittled down to a list of 70 that were voted on to yield a shortlist of 25 questions for discussion and further ranking by the group. The research priorities that were ranked 'top 10' have been sent to the National Institute for Health Research Evaluation, Trials and Studies Coordinating Centre, to feed into the process of determining where research funding should be directed.

How does the HTA work?

Friday, 27 February 2015 16:20

The first of a series of articles from Professor Tom Walley, Director of the NIHR HTA Programme, covers how the HTA staff prioritise topics for research and for funding.

NIHR's Benefits Advice Service for involvement in research activities

Tuesday, 03 February 2015 09:38

A new confidential service has been launched offering personal advice and support on how payment of fees and expenses for public involvement might affect people in receipt of state benefits. In partnership with others, NIHR is offering a service that covers advice on payment of fees and expenses for public involvement in health or social care research, service design or service delivery. The service will be provided by Bedford Citizens Advice Bureau, initially as a pilot for one year. The confidential service is for members of the public involved with NIHR organisations or NIHR funded research projects and for staff within NIHR organisations who are supporting members of the public to get involved. Further information is available on the INVOLVE website.

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