Research News

Cambridge MRC Cancer Research Unit release 'pill on a string' for diagnosing oesophageal cancer

Wednesday, 22 July 2015 07:21

Julie Solomon, BSG Head of Research and Learning

BSG member Professor Rebecca Fitzgerald and her team have developed a less intrusive but more effective way to sample the cells lining the oesophagus. This method uses the CytoSponge™, a compressed open-fibre sponge that opens up once in the throat and can be retrieved easily using an attached cord. The open texture and size of the sponge increase the probability of finding pre-cancerous tissue that might otherwise have been missed by more conventional endoscopic biopsy techniques. An additional benefit of gathering more tissue has been the ability to track changes in the cells that could indicate a change to cancerous tissue. Detecting these changes early is essential, because oesophageal cancer is very difficult to treat. [Professor Fitzgerald won the UEG Research Prize in 2014 for the project to develop CytoSponge™: "Combination of quantifiable genomic assays with a patient friendly non-endoscopic cell retrieval device called Cytosponge™ for management of patients with Barrett's oesophagus".] The BSG congratulates Professor Fitzgerald on her achievements.

Gastroenterology-led TRIGGER trial of transfusion strategies for GI bleeding published in the Lancet

Wednesday, 15 July 2015 12:38

TRIGGER is a multicentre randomised pilot trial comparing red blood cell transfusion strategies for Acute Upper Gastrointestinal Bleeding (AUGIB). Through the examination of liberal and restrictive policies for transfusion, TRIGGER established that, with further research, the way AUGIB is treated in the UK could change significantly, benefitting patients and producing significant cost savings for the NHS.

This work directly followed on from the British Society of Gastroenterology (BSG)-supported UK national audit of GI bleeding, which was led by Kel Palmer and others. The trial was delivered through a successful collaboration within and between UK gastroenterology centres and other groups. Prof John McLaughlin, the BSG's Research Committee Chairman while the trial was being carried out, said "This fantastic piece of work shows the power of collaborative research. Hopefully the NIHR will support a follow-on study of restrictive transfusion for AUGIB, which has the potential to benefit individual patients and the NHS as a whole."

Alcohol-Related Liver Disease research: survey

Tuesday, 07 July 2015 12:40

Do you have a question about the diagnosis, prevention, care or treatment of alcohol-related liver disease (ARLD)? Are you, or someone you know, affected by or worried about ARLD? Would you like to have a say in guiding research into ARLD?

The National Institute for Health Research (NIHR) and British Society of Gastroenterology (BSG) have opened a survey to collect important information to help prioritise unanswered questions about ARLD. The survey gives patients, carers, clinicians and family members affected by the disease an opportunity to have their say and influence future research in the area. Please complete the survey yourself and give the link to anyone who might be interested in contributing.

UEG Research Prize - Winner 2015

Monday, 06 July 2015 09:15

Professor Jan Tack, Leuven, Belgium

Jan Tack is Head of Department of Clinical and Experimental Medicine at the University of Leuven (Belgium). He is awarded the UEG Research Prize 2015 for his pioneering work in the care of patients with functional and motility disorders, focussing in particular on functional dyspepsia, and the endeavour to identify novel ways to treat these disorders.

The Prize will support Jan Tack’s research group “The Gastrointestinal Motility and Sensitivity Research Group” with its research project “Role of nutrients and tastants in determining the gastric accommodation (GA) reflex and the control of meal volume tolerance in health and disease". The aim of this project is to unravel the pathways underlying the recently discovered role for gastric nutrient sensing in the control of gastric accommodation - a research which is furthermore promising to identify novel ways to combat obesity and to find therapeutic approaches to body weight control as well as to functional and motility disorders.

Jan Tack will receive the Prize at the Opening Plenary Session of UEG Week Barcelona on Monday, October 26, 2015.

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