The Inflammation Revolution: A Translational Science Masterclass
BSG 2014 will host Scientists in Gastroenterology's first Translational Science Masterclass, a full day symposium aimed at reconnecting UK clinicians and basic scientists in key areas of Gastroenterology and Hepatology research.
With huge recent advances in post-genomic science, gut and liver immunology, and the growing realisation of the importance of the microbiome to human health and disease, the first event will focus on these cross-cutting themes, with a strong Faculty of local, national and international speakers.
Where better to start our revolution than the city where the industrial revolution began, the atom was split and the first computer was created. We hope to see you there!
John McLaughlin, Chair, BSG Research Committee and Sheena Cruickshank, Scientists in Gastroenterology.
Join us on 19th June 2014 at BSG 2014 at the Manchester Central Convention Complex, UK
- Download programme [ 13 kb ]
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BSG members win substantial funding for clinical trial
Tuesday, 07 January 2014 15:22
Several BSG members were co-applicants on a recent successful application for substantial funding of a clinical trial in hepatology. Prof Mark Thursz, Dr Steve Ryder, Prof Matthew Cramp, Dr Paul Richardson and Dr Stuart McPherson are among a group represented by Dr Alastair O’Brien. The group received £1.6 million from the Health Innovation Challenge Fund (joint Wellcome Trust and Department of Health) for ATTIRE (Albumin To prevenT Infection in chronic liveR failure).
The money will fund a multi-centre, clinical, phase II and phase III trial at 15 sites that will examine whether administration of albumin to patients admitted with decompensated liver failure, in order to increase plasma levels to near normal, will prevent hospital acquired infection. Dr O'Brien's local clinical research network (LCRN) will fund the research nurse costs (>£1million).
Over 100,000 patients are admitted to hospital every year with advanced liver cirrhosis; infection is their most common problem. Dr O’Brien and his team have shown that, in these patients, leukocyte function is markedly impaired by an up-regulation of the hormone Prostaglandin E2; infusion of albumin can reverse this process by binding and neutralising its effects. Albumin is widely considered by hepatologists to be beneficial in liver disease but no putative mechanism had been identified, so no consensus had developed for how to prescribe it. Dr O’Brien and colleagues aim to repurpose albumin as an immunity-restoring drug to improve leukocyte function in patients with advanced cirrhosis and therefore improve their ability to fight off infection. They hope to demonstrate that its use will lead to reduced rates of nosocomial infection and mortality and shorter hospital stays, thereby reducing health care costs.
Paediatric European Digestive Diseases Clinical Research Network (PEDDCReN) Survey
Tuesday, 10 December 2013 14:18
Nick Croft, Julian Thomas, Nikhil Thapar (UK Members of the PEDDCReN Steering Group) and Varsha Tailor (PEDDCReN Project Manager) invite you to participate in a 5-minute survey that will allow the project team to identify the interests of the departments across Europe, in order to determine what expertise and resources are available for setting up and running clinical trials in this speciality. For further details and access to the survey itself, please click here.
Graham Bull prize in clinical science and Goulstonian Lectureship 2014
Tuesday, 26 November 2013 11:53
The Graham Bull prize was established in 1988 in honour of Sir Graham Bull, who was the first director of the Clinical Research Centre at Northwick Park. A trust for the Graham Bull Prize was set up to provide money for young research workers under the age of 45 who feel that they have made a major contribution to clinical science. The prize as designed by the trust is specifically for an application and not for nomination of individuals. The work can cover a wide range of expertise, such as molecular and cellular biology, imaging technology, psychiatry, or health sciences. The award is open to RCP members and fellows who must apply for their own work to be considered. The sum of £1,000 is offered on a competitive basis each year.
The winner of this prize will also be invited to deliver the Goulstonian Lecture, an annual lecture endowed in 1635 by Mrs Ellen Goulston in memory of her husband, Dr Theodore Goulston FRCP.
Researchers under the age of 45 years. Must be a member or fellow of RCP London.
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