Research News

Registered Clinical Trials Units

Friday, 27 November 2015 12:02

The UK Clinical Research Collaboration (UKCRC) Registered CTU Network is a network of academic clinical trials units (CTUs) that have been assessed by an international panel of experts in clinical trials research. This site is the authoritative web resource for information about the UKCRC Registered Clinical Trials Units. The information provided on this site is aimed at the following groups, both within and outside the UK:

  • Clinical researchers and investigators
  • Clinical research networks
  • Funders of clinical research (both industry and non-industry)

    The site offers a resource for clinical researchers and funders wishing to identify CTUs that have expertise in centrally coordinating multicentre clinical trials, as well as in trial design, data management, and analysis. It provides comprehensive information and direct access to high quality CTUs across the UK which have achieved UKCRC Registration status.

  • Focus group tackles better outcomes for EU cancer patients

    Friday, 20 November 2015 10:34

    Press Release: Brussels, 19 November 2015 More than 1.75 million citizens die from cancer every year in the EU, and Europe’s ageing population will significantly increases the incidence of cancer over the next two decades.

    The Brussels-based European Alliance for Personalised Medicine (EAPM) has published a series of articles in an international online health magazine as part of the work of its EU Consensus Group on Clinical Trials. The articles have appeared in a special edition of Public Health Genomics under the title Getting Personal: The Future of Medicine and Clinical Trials. This is the first stage of the multi-stakeholder team’s activity and their articles attempt to address whether a personalised medicine-enabled clinical research and trial strategy can produce better outcomes for cancer patients across Europe’s 28 Member States. The second stage of their activity will be prioritising the challenges and proposing workable solutions.

    The authors have stated that “Now is the time to deliver focused solutions that will improve outcomes for cancer patients in Europe.” An important part of the work undertaken by EAPM concerns clinical trials and patient access to them. Indeed, one of the four-year-old Alliance’s main aims is tackling the broader issues of personalised medicine in terms of clinical trials, as well as biobanks, data sharing, EU regulations and more, while looking towards the EU’s Horizon 2020 initiative.

    Clinical trials are vital to patients and the advancement of cures for a multitude of diseases, but the issues surrounding countrywide and, even more so, pan-European trials and their application in modern-day medicine are complex.

    The consensus panel was brought together in an attempt to define how personalised medicine cancer clinical trials should be organised in order to direct patients to the most appropriate research as well as addressing important unmet needs.

    One crucial issue is the question of how clinical trials should best be run to maximise the effectiveness of personalised medicine initiatives which make the best provision for access for appropriate patients.

    Another main aim is to determine how to structure cross-border clinical trials by enabling collaboration and minimising regulatory burdens.

    And a further goal is to determine how to solve the problem of ensuring that clinical trials can be held and financed in the most efficient way possible.

    From an original roundtable in Madrid, EAPM’s EU Consensus Group has since held a series of face-to-face meetings and telephone conferences in order to identify key challenges.

    These involve the reality that: the cancer drug development model is no longer fit for purpose; the traditional clinical trials framework does not support a personalised medicine strategy, and; escalating costs of cancer health care undermine clinical innovation.

    The panel also found that a lack of clinically validated biomarkers hampers a personalised medicine-enabled approach, and that current European legislative reform threatens clinical cancer research.

    Meanwhile, they say, a lack of understanding and insufficient patient involvement undermines participation in clinical research, while an absence of cooperation between different stakeholders lessens the effectiveness of personalised medicine implementation.

    The articles are available to read at the following link.



    Denis Horgan, EAPM Executive Director, EAPM, Avenue de l'Armee/ Legerlaan 10, 1040 Brussels, Belgium Ph: + 32 4725 35 104 Website:

    About EAPM

    The European Alliance for Personalised Medicine brings together Europe's leading healthcare experts and patient advocates to improve patient care by accelerating the development, delivery and uptake of personalised medicine and diagnostics. It is calling for the European Commission, the European Parliament and EU member states to help improve the regulatory environment so that patients can have early access to personalised medicine, and so that research is boosted.

    MRC guidance on obtaining data from the Health and Social Care Information Centre

    Thursday, 19 November 2015 16:12

    The MRC Regulatory Support Centre has been working in partnership with researchers and regulators to develop a number of resources that support health informatics research. These can be found on the MRC website. This page launches the latest guidance "Obtaining data from the Health and Social Care Information Centre (HSCIC) for health research". Following on from the barriers analysis conducted earlier in the year, this practical guide for researchers includes tips on obtaining the necessary approvals. It was developed jointly with the HSCIC and will be a living document, updated regularly as HSCIC processes evolve. The latest version is dated 28/10/2015.

    Crick Cancer Clinical Research Fellow Programme

    Wednesday, 11 November 2015 15:23

    Applications are invited for three clinical research fellows to conduct research related to cancer. These posts will provide the opportunity to perform innovative research in the newly established Francis Crick Institute in London. Further details of the context, organisation, person specification, application process and projects are available to download. The application deadline is Sunday 6 December 2015. Interviews will be held in early February 2016. Informal enquiries can be directed to This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

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