STOPAH (Steroids or Pentoxifylline in Alcoholic Hepatitis) is a multicentre UK trial funded by NIHR-HTA. This is a vital study in UK hepatology looking to prove the role of steroids or pentoxifylline versus placebo in the treatment of a condition which is increasingly common in the UK. Patients with DF>32 are eligible and the study is designed to be pragmatic with few exclusions to treatment. Primary outcome is 30 day mortality but with follow-up to a year.
Update: March 2011
This has been delayed partly due to issues regarding trial drug provision. A hub-and-spoke distribution provides the most cost-efficient method of provision, but has caused some logistical difficulties at a local level. However, these are starting to be resolved and the first patients are now being recruited. Please contact the CI or trial coordinator if you are interested in taking part. .