Research

Paediatric European Digestive Diseases Clinical Research Network – PEDDCReN

PEDDCReN was an exciting new initiative with the key aim of forming a clinical trials network to study (and ultimately provide) effective medicines for paediatric patients in the speciality of Gastroenterology, Hepatology and Nutrition. It was established with the support of LINK funding from the UEG and was led by the BSG in collaboration with various European societies and ENPR-EMA (The European Network of Paediatric Research at the European Medicines Agency). The project supported both industry and non-industry investigators in running high quality multi-centre clinical trials. The final report has now been published.

HCV clinical trial and tissue biobank

HCV Research UK is a national cohort of over 11,000 patients enrolled between 2012 and 2014 from 60 centres within the UK with evidence of hepatitis C virus infection. All patients have enrolled with written informed consent, which allows storage of routinely collected clinical data in a linked-anonymised database, and have donated biological samples to a biorepository (held in Glasgow).

The purpose of HCV Research UK is to act as a resource to support research into a range of aspects of HCV infection.

Applications for access to data and/or samples may be made through the HCV Research UK Tissue and Data Access Committee through completion of an on-line application form.

Further details may be found at www.hcvresearchuk.org

IBD Nixon Twin and Multiplex Registry

UK gastroenterologists are invited to refer concordant and discordant twin pairs, as well as families where three or more first degree relatives have an IBD diagnosis, to the twin/multiplex registry. They will collect epidemiological data and invite members to donate blood, urine and stool samples to a biobank. This will become a powerful research resource that will be available for research collaborations in the future.

Further information about how to refer twins or families is available from Dr William Blad, IBD Nixon TAM Registry Co-Investigator, Chelsea and Westminster Hospital, This e-mail address is being protected from spambots. You need JavaScript enabled to view it

ENDCaP-C Study: Enhanced Neoplasia Detection and Cancer Prevention in Chronic Colitis

CRN West Midlands is the Lead CRN for the ENDCaP-C study (Enhanced Neoplasia Detection and Cancer Prevention in Chronic Colitis: A Multicentre test accuracy study; UKCRN ID: 17739; Chief Investigator: Dr Tariq Iqbal). The study team would like to open an additional 10 sites nationally in order to reach their ambitious recruitment targets and identify more potential PIs. If you or your site might be interested in becoming involved, please review the trial summary and study detail and contact either James Brown or Steve Johnson via This e-mail address is being protected from spambots. You need JavaScript enabled to view it to discuss the study further.

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