Research

New Centres Sought for C.Difficile Study

The RAPID trial is looking to open more recruitment centres. We are examining the effectiveness of Rifaximin in preventing recurrence of C.difficile infection. Professor Robin Spiller is the Chief Investigator of this NIHR portfolio study (UKCRN ID: 12990), being sponsored by the University of Nottingham.

To express interest and receive more information, please contact Nafisa Boota (Trial Manager, Nottingham Clinical Trials Unit). Telephone: +44 (0)115 884 4924. Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

Paediatric European Digestive Diseases Clinical Research Network – PEDDCReN

PEDDCReN is an exciting new initiative with the key aim of forming a clinical trials network to study (and ultimately provide) effective medicines for paediatric patients in the speciality of Gastroenterology, Hepatology and Nutrition. It was established with the support of LINKS funding from the UEG and is led by the BSG in collaboration with various European societies and ENPR-EMA (The European Network of Paediatric Research at the European Medicines Agency). The project will support both industry and non-industry investigators in running high quality multi-centre clinical trials and your involvement is welcome.

 

Clinical Research News - Network Structure from April 2014

Tuesday 25th June 2013

Earlier this year BSG members kindly responded to a consultation exercise conducted by the National Institute for Health Research Clinical Research Network.

The consultation asked for views about how best NIHR could structure the Network to ensure that they:

  • Maximize clinical engagement in research delivery
  • Provide an effective service for researchers and research funders, within the context of a changing NHS
  • Continue to increase the opportunities to engage patients in clinical research

The responses were extremely useful in helping to determine their future structure, NIHR would like to thank you for your input, and let you know that they have now issued the “map” of their new structure from April 2014 onward.

Maintaining a specialist focus on research delivery in different therapy areas was a key priority in considering their future state, so NIHR have kept, and even built upon, this aspect in their plans. NIHR will be introducing any changes gradually, and will communicate with their stakeholders as they go forward, but for now please continue to work with your usual Network contacts in the usual way.

You can read about the revised structure at: www.crncc.nihr.ac.uk/nihrcrnstructure

 

Good news: significant performance improvements

Heather Slade, acting Head of Research Management and Governance at the CCRN, recently wrote to the Specialty Group Chairs to congratulate them on improved performance figures for the study approval process. "The process for providing NHS permissions (CSP) within study set up has undergone some significant service reviews and improvements over the last twelve months. We are very pleased with the improvements we have delivered - the average time to complete study wide reviews and the average time to complete local reviews were just 21 days for 12/13, a five-fold improvement on previous years... obtaining R&D approvals is very rarely the block that it used to be... researchers [should] understand that they should get planning much earlier than they used to in order to be ready to recruit patients after a rapid approval... There is much to celebrate and we would like to thank you and your Specialty Group for the huge role you have played, and continue to play, in supporting the successful delivery of research in the NHS."

If you have examples of rapid approvals or other ways in which the CRN has helped with study set-up (eg site identification and the rapid deployment of staff), please send them by 23rd July to This e-mail address is being protected from spambots. You need JavaScript enabled to view it . It would be helpful if examples could include reference to:

1. Title of study and UKCRN ID
2. What your role was with the study: CI/PI etc.
3. By which Specialty Group was the study led?
4. How quickly did the CSP and NIHR teams deliver NHS permissions for this study?
5. Did the network help in other ways with study set up?
6. What impact did this have on the overall delivery of the study?

Clinical Trial Details from the NIHR

The NIHR has now made a public-facing version of the UK Oral and Gastrointestinal Study Portfolio; here you can access details of GI and hepatology studies that are recruiting or are being set-up, as well as those that have closed or been suspended. Studies can be searched by country (England, Northern Ireland, Scotland or Wales) and by various other criteria. A user guide is available via a link on the site. Output can be exported to Excel for easy reference. This information should be updated on a frequent (at least monthly) basis, and covers all trials in the portfolio. Any BSG member who wishes to call particular attention to a study (via the BSG's website or e-news) should send a brief summary with all relevant details, deadlines and contact information to This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

If you are a patient or carer, or perhaps a member of the public with an interest, you can help research. You could become a participant in a clinical research study that may benefit many people. You could even help shape clinical research by becoming more actively involved and having a say. Access information about the importance of clinical research, taking part, and how you could help influence the research that gets carried out.

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