BOSS (Barrett's Oesophagus Surveillance Study)
BOSS. Barrett’s Oesophagus Surveillance Study. Endoscopic surveillance vs no endoscopic surveillance for the prevention of early mortality in patients diagnosed with Barrett’s oesophagus. Patients randomized to receive endoscopy with biopsy every two years for 10 years or endoscopy at the time of need. All patients receive a bi-annual postal questionnaire to record their symptoms and other health related data (administered by the centre). Patients followed up for 10 years. Sample size = 2500.
Update: March 2011
We have 109 hospitals opened to recruitment, we are more than happy to accept other hospitals if they wish to join us. We are currently in negotiations with the HTA to increase our numbers from 2,500 to 3,400.
Take home message: " BOSS is recruiting at a fast pace now thank s to all our colleagues across the UK, please keep this up".