Research Funding Opportunities
Funding opportunity: Coeliac UK
Coeliac UK, the leading national charity for people with coeliac disease and dermatitis herpetiformis, is launching a new round of research grant awards with up to £200k of funding available.
Researchers from all scientific disciplines are invited to submit applications that can demonstrate how their proposal will advance our understanding of the disease and improve the lives of those living with the condition.
Please visit the Coeliac UK website for further information and to download an application form: www.coeliac.org.uk/researchcall
CICRA Research Grants
The Crohn's in Childhood Research Association offers the following research opportunities.
Research Fellowship in Paediatric Gastroenterology: Applications are invited from interested centres in the UK - closing date for receipt of applications Thursday 6th November 2014
PhD studentship: CICRA invites applications from research groups with a proven track record of high quality output in gut immunology and inflammation or IBD genetics. Closing date for receipt of applications - Thursday 6th November 2014
Project grant: CICRA invites high quality research applications for funding up to £100,000 relevant to Crohn’s disease or ulcerative colitis in childhood. Closing date for receipt of applications Thursday 6th November 2014
Bursary grants: CICRA also gives grants of up to £400 (up to a total amount of £5,000pa) to enable UK based young Doctors still in training/nurses/final year medical students and similar persons with an interest in the area of Crohn's and colitis (IBD) to support attendance at national, international scientific/educational congresses and if considered appropriate IBD related training courses.
Application forms and further information can be obtained from the CICRA website: www.cicra.org
HTA commissioned funding opportunity 14/161 - Fibre for uncomplicated symptomatic diverticular disease of the large bowel
The HTA is accepting applications to this commissioned call. The research question is 'What is the clinical- and cost-effectiveness of prescribable fibre supplements to treat uncomplicated symptomatic diverticular disease of the large bowel?' Although low intake of fibre is associated epidemiologically with an increased risk of developing diverticulosis, the recommendations for fibre as a treatment are based on weak evidence that is old, largely observational, and uncontrolled. There is also no good evidence for the amount or type of dietary fibre needed, and clinical experience suggests that bran fibre and green vegetables may worsen symptoms in some patients. This fits with data from randomised controlled trials in irritable bowel syndrome showing that bran increases flatulence. However, high fibre diet is often recommended in advice for patients, and fibre is prescribed in the NHS. To address the uncertainty over the use of fibre in uncomplicated but symptomatic diverticular disease a trial to evaluate prescribable fibre is required. Many patients may have already been prescribed fibre so a trial could examine the benefits and harms of withdrawal of prescribed fibre as well as introducing it.The application deadline is 1pm on 18 December 2014. Further guidance is available.
HTA commissioned funding opportunity 14/166 - Prevention of parastomal hernia formation
Is prophylactic mesh effective for the prevention of a parastomal hernia during primary permanent stoma formation? The HTA is accepting applications for funding in this area. The morbidity associated with stoma formation is a considerable problem for the NHS. Use of a prophylactic mesh during the primary operation may reduce the incidence of parastomal hernia (PSH) formation. However, it is believed that a mesh only delays the presentation of a PSH in the short to medium term rather than prevent it completely, and formation of a PSH may be the result of a number of cumulative factors. Currently, there is no established method of mesh placement, no surgical consensus concerning which material the mesh should be made of and the type of aperture (if any) that should be cut into the mesh. There is also disagreement as to whether to use mesh at all. A prospective cohort study is needed to explore the different approaches to preventing a parastomal hernia forming during primary permanent stoma formation and to identify any interventions that may be appropriate to investigate in a future randomised controlled trial.
The deadline for applications is 1pm on 18 Dec 2014. Further guidance is available to download.
Research for Patient Benefit (RfPB): Researcher-led proposals
Both Competition 25 and an RfPB Themed Call - Long-term Conditions in Children and Young People opened on 25 June 2014 with a closing deadline of 1pm on 17 September. Applications to the RfPB Programme should arise from daily practice in the NHS and must demonstrate a trajectory to patient benefit in the short to medium term. The programme supports applications, which are regionally derived, and applications for feasibility and pilot studies are welcome. More information is available from the RfPB website.
HTA commissioned funding opportunity 14/28 - Covered versus uncovered self-expanding metal bowel stents
Colonic stenting allows relief of an obstruction while avoiding stoma formation in palliative cases. The potential complications associated with stenting include perforation, stent obstruction and stent migration. Patients receiving a stent for palliation have the stent inserted as a definitive procedure and determining the efficacy and complications of different stent designs is very important in this group.
A recent systematic review concluded that tumour ingrowth was more common with uncovered stents, but that late migration occurred more frequently with covered stents, and expulsion causes significant morbidity. However, the authors noted that there was potential for publication bias and that the evidence was very limited as there has only been one small, single centre RCT to date. Consequently, the authors recommended definitive primary research to compare covered and uncovered stents in order to assess their clinical and cost-effectiveness.
Further details and guidance notes are available to download. The application deadline for this two-stage (outline to full proposal) funding call is 1pm on 14 August 2014. Supporting information is also available from the HTA website.
Proposed research areas for 2014/15 HTA commissioned calls
HS&DR commissioned funding opportunity 14/156: New research on use and usefulness of patient experience data
Quality of care can be measured not just by the treatment received and changes in patient outcome, but also the way in which that care was delivered. To date, this has been assessed quite crudely by broad patient satisfaction surveys or global rating measures. All health and care organisations are now required to collect data on patient experience, in the form of national standards in the domain on patient experience in the NHS Outcomes Framework. Overall, there is little UK-based research on how best to make use of patient experience data or what organisations can do to ensure that patient feedback shapes services and care. Thus, the topic of use of patient experience data was highlighted as a top priority for the HS&DR programme in two consecutive years by clinicians, patients, service leaders and managers. This topic was further refined at discussion at a workshop in February 2014, where the focus was on making patient experience data usable and useful to the service. Further information relating to this funding call is available to download. Applications are due by 1pm on 11 September 2014.
EME researcher-led funding opportunity 14/150
The EME Programme is accepting applications to its researcher-led workstream. Applicants are invited to apply by 1pm on 30 October 2014. More information on how to apply can be found on the EME researcher-led call webpage.
EME commissioned funding opportunity 14/144: Bowel control and faecal incontinence in adults
The EME programme is accepting applications to its commissioned workstream for proposals in bowel control and faecal incontinence in adults. Proposals are sought for studies into interventions to improve bowel control in adults of any aetiology, and particularly those designed to prevent, treat or alleviate the occurrence of faecal incontinence. Applications must concentrate on determining the clinical efficacy of interventions, but the inclusion of embedded mechanistic studies within the main clinical evaluation is strongly encouraged. Studies of mechanical interventions are unlikely to be supported unless they include a significant mechanistic component.
More details are available to download; the call closes at 1pm on 7 October 2014.
Proposed research areas for 2014/15 EME commissioned calls - updated 1 July
Please note that research in the following broad areas is likely to be commissioned during the next year, although the titles and timings may be subject to change. The individual commissioning briefs, which will be published when the calls open, will define the details of the calls.
Novel endoscopic optical imaging interventions and technologies: anticipated opening date October 2014
Inflammatory bowel disease: anticipated opening date October 2014
Metabolic liver disease (including NAFLD): anticipated opening date February 2015
Invention for Innovation (i4i) Programme
The 8th call for i4i Product Development Awards closes on 9 July 2014 at 1pm. i4i will support projects developing any innovative medical technology including medical devices, active implantable devices and in vitro diagnostic devices. i4i will also support projects which utilise and develop techniques or technologies from other industry sectors that could have a potential impact if applied in a healthcare setting.
The opening date for the 4th call for i4i Challenge Awards will be 9 September 2014. The i4i Challenge Awards is a new i4i funding stream that aims to bridge the gap between the innovation and development of new medical technology and its adoption into clinical pathways. For details and to apply, go to the i4i homepage.
Pump prime funding for initial feasibility studies
NIHR Enteric HTC aims to identify and address unmet clinical need in the diagnosis and management of disorders of the gastrointestinal tract and bowel function. The HTC seeks new ideas for medical device innovations and offers the opportunity to apply to NIHR Enteric HTC for pump prime funding for initial feasibility studies on potential new medical technologies within the field of digestive diseases and GI surgery.
- Further information[ 33 kb ]
MRC Public Health Intervention Development Scheme (PHIND)
The Public Health Intervention Development scheme (PHIND) is a new MRC funding scheme designed specifically to provide support for early phase development of public health interventions. This rapid response funding scheme is aimed at improving the initial evidence on which the development and evaluation of public health interventions are based. Studies should address an important UK or global public health issue and offer an innovative approach to intervention development or applying an existing intervention in a new setting.
The scheme's remit ranges from primary research developing and designing the intervention to feasibility studies, encompassing:
- developing theory
- modelling process and outcomes
- assessing feasibility
Systematic reviews, meta analyses and pilot studies are outside the remit of the PHIND scheme. Applicants can apply for up to £150K for a maximum of 18 months and the scheme will operate three times a year. For further information, please see the MRC website.
National Institute for Health Research (NIHR) Funding opportunities booklet
This booklet provides information about the NIHR’s research funding and career development opportunities available for researchers based in the NHS, universities, industry and other organisations concerned with health, public health and social care.
A brief overview of the National Institute for Health Research (NIHR)
This leaflet provides an overview of the structure and work of the National Institute for Health Research.
The NIHR has published various documents in which you might be interested. They are available here.