Clinical News

BSG supported STOPAH study shows a lack of evidence for drug treatments

Wednesday, 29 April 2015 08:22

The survival of patients with alcohol-related hepatitis is not being significantly improved by the main drugs currently widely used in treatment of this condition, according to a major new National Institute for Health Research sponsored study supported by members of the British Society of Gastroenterology.

Senior health professionals are highlighting an 'urgent need' for investment into research for the prevention and treatment of alcohol-related liver disease. Documented in the New England Journal of Medicine¸ a trial of over 1,000 patients using prednisolone and pentoxifylline did not achieve a statistically significant reduction in mortality after 28 days, 90 days, or a year.

The alarming findings come at a time when the incidence of alcohol-related liver disease is rapidly increasing, however the report does also show that the overall mortality has fallen compared to studies done in the past which suggests that specialist in hospital care of these very sick people can improve outcomes, and what could be achieved more widely contrasting with the 2013 NCEPOD report on the care of cirrhosis where care was often found to be lacking.

Commenting, British Society of Gastroenterology Vice President (Hepatology), Dr Stephen Ryder, said:

"STOPAH has answered some key questions in the treatment of alcohol-related hepatitis and highlighted the urgent need for research into the prevention and treatment of alcohol-related liver disease, which is on the rise.

Whilst the study does suggest that patients are receiving better care than reported in previous reviews, unfortunately it also shows that neither steroids or pentoxifylline are effective treatments and there is no real indication now for their use.

The stark finding in STOPAH remains the high late mortality related to resumption of alcohol intake and emphasises the need for universal implementation of the BSG recommendations on alcohol care teams, that seems likely to be a far more effective intervention than any medical therapy for the acute episode.

One of the great successes of this study was to show that UK hepatologists and gastroenterologists from over 50 UK centres can collaborate to deliver important large scale clinical studies aimed at improving outcomes for patients with liver disease."

 

IBD Registry News – April 2015

Tuesday, 31 March 2015 14:10

IBD Registry Web Tool
The IBD Registry Web Tool is just about to be released to pilot sites Liverpool and Inverness.
The tool will give clinicians who are unable to use the PMS an opportunity to participate in the Registry, while still benefitting from useful local outputs such as GP letters and patient summaries.

The system also includes the biologics audit data and can generate a biologics work list, so clinical teams will be able to enter their biologics audit data prospectively at the point of clinical contact. We anticipate the Web Tool will be available for general uptake in England in summer 2015, and the rest of the UK later in the year. To view a test version, please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

Consent Materials Now Available
Adult and paediatric patient information leaflets, consent forms and posters are now available, as well as a document explaining your responsibilities as participating IBD Registry centres. Please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Anaemia Project
Our first collaborative project looking a specific topic has recently been set up. The IBD Registry and Pharmacosmos are partnering to trial the use of a specially-adapted page of the web tool to collect data on iron-deficiency anaemia in patients with IBD.

DDF Save The Date!
Thursday 25th June 11-1 at DDF
IBD Registry chair Stuart Bloom and IBD Audit clinical lead Ian Arnott will co-chair an interactive session: IBD in the UK, Improving Patient Outcomes and Experience.
With a panel discussion chaired by the Guardian's executive editor Jonathan Freedland, the meeting will identify what needs to be done to make sure all IBD patients receive world class care regardless of where they live in the UK.
The 2015 IBD Registry data will be presented, including for the first time data from sites using not only the PMS but also the web tool and third party systems.

Get Involved
We're planning an update of the IBD Registry website later in the year. We'd love to hear your feedback on the site: what's missing? what information would you like to see?

To find out more about joining the Registry click here or email This e-mail address is being protected from spambots. You need JavaScript enabled to view it

UEG is calling on all EU countries to evaluate advanced CRC screening techniques to help increase survival rates

Tuesday, 17 March 2015 10:14

The Colorectal Cancer Awareness month kicks off UEG's latest campaign "Screening Saves Lives (CRC) 2015". Colorectal cancer accounts for about half of all gastrointestinal malignancies in Europe and the annual incidence is predicted to rise by 12% by 2020. UEG is calling on everyone over 50 to 'Step Up, Take the Test'. Read full press release and follow this campaign on Twitter #ScreeningSavesLives.

Nice Quality Standards for IBD

Friday, 27 February 2015 10:42

Professor Chris Probert, Chair BSG IBD Section Committee

"The BSG welcomes the release of Quality Standards for IBD by NICE. The four statements are necessarily succinct and members should read the more detailed version on the NICE website. This document sets a standard that should be recognised by CCGs and Trusts and should enable us to raise the quality of our services. These standards should form the basis of the forthcoming IBD Accreditation, along with the IBD Audit and Registry."

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