Clinical News

New liver disease atlas shows major variation across England

Thursday, 26 October 2017 10:18

New data published by Public Health England shows a wide variation of premature mortality rates from liver disease across England. Liver disease is almost entirely preventable with the major risk factors, alcohol, obesity and Hepatitis B and C, accounting for up to 90% of cases. The atlas will help health professionals to allocate their resources to improve patient outcomes.

The atlas shows premature mortality rates - dying before the age of 75 - ranged from 3.9 per 100,000 in South Norfolk clinical commissioning group (CCG) to 30.1 per 100,000 in Blackpool CCG, a 7.7 fold difference. The atlas paints a mixed picture, with 10 indicators showing improvements including a reduction of premature deaths and fewer alcohol-specific hospital admissions for under 18s.

Nine of the indicators have become worse over time, including a doubling of hospital admission rates for cirrhosis from 54.8 per 100,000 to 108.4 per 100,000 people over the past decade. This indicator also varies significantly across the country with an 8.5 fold variation across CCGs and this gap has widened over the past decade. Liver disease is responsible for almost 12% of deaths in men aged 40 to 49 years and is now the fourth most common cause of 'years of life lost' in people aged under 75, after heart disease and lung cancer.

Professor Julia Verne, Head of Clinical Epidemiology at PHE said:

"Chronic liver disease is a silent killer of young adults, creeping up and showing itself when it's often too late. However, around 90% of liver disease is preventable."

"We hope local health professionals will make the most of this rich data source to inform how they reduce the burden of liver disease in their areas."

The atlas also lays bare the impact of the stark health inequalities in England. Inequality plays a role in the significant variation in risk factors of liver disease - excessive alcohol consumption, obesity, and hepatitis B and C. For example, there is a 7.4 fold difference in the rate of alcohol-specific hospital admissions across the country, with the majority of the higher rates being clustered in the more deprived areas. Also, in the most deprived fifth of the country, people with liver disease die 9 years earlier than those in the most affluent fifth.

These data will underline the importance of developing a strategy to tackle the rising burden of liver disease, especially in younger adults and even children. Liver disease can take 20 years to show up as symptoms.

The atlas is made up of 39 indicators, 19 of which show trend data over time. It shows the degree of variation across the country, a national figure for comparison and commentary providing options for action and a list of evidence based resources for local health systems to improve.

NICE: Medical Technologies Advisory Committee

Tuesday, 10 October 2017 09:24

NICE are looking for members to join the Medical Technologies Advisory Committee.

Closing date: 5pm, Thursday 26 October 2017.
Time commitment: 3 years

NICE are looking for:

the following specific roles:

  • a HTA or health service researcher
  • a secondary care clinician, particularly those with an interest in innovative technologies
  • a diagnostics specialist
  • a senior manager.

Any questions? Contact Pratixa Patel at This e-mail address is being protected from spambots. You need JavaScript enabled to view it

IBD Registry News: October 2017

Monday, 02 October 2017 14:04

The latest news from the IBD Registry can be found at the further information link below. Updates include:

  • Patient Consent Update
  • Data & Reporting
  • Resources
  • Opportunities

IBD Registry News: September 2017

Thursday, 31 August 2017 12:08

The latest news from the IBD Registry can be found at the further information link below.

  • Drug Dictionary Medication Update
  • Registry Participation
  • Quarterly Data Submission and Reports
  • IBD Registry announces Field Support Programme
  • Caldicott Guardian Opportunity
  • IBD Nurse & SpR Programmes

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